ALDH2 抗体
Quick Overview for ALDH2 抗体 (ABIN5700232)
抗原
See all ALDH2 抗体适用
宿主
克隆类型
标记
应用范围
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免疫原
 - aldehyde dehydrogenase 2 family (mitochondrial)
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亚型
 - IgG
 
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应用备注
 - WB :1:500-1:5000,IHC:1:20-1:200,IF:1:50-1:500,IP:1:500-1:5000
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说明
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mouse lung tissue were subjected to SDS PAGE followed by western blot with FNab00291(ALDH2 antibody) at dilution of 1:1000
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限制
 - 仅限研究用
 
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缓冲液
 - PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
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储存液
 - Sodium azide
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注意事项
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
 - Avoid repeated freeze / thaw cycles.
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储存条件
 - -20 °C
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有效期
 - 12 months
 
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- ALDH2 (Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2))
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别名
 - ALDH2
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背景
 - Synonyms:ALDH class 2, ALDH E2, ALDH2, ALDHI, ALDM Background:This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50 % of East Asians have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among East Asians than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
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分子量
 - 56kDa
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基因ID
 - 217
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UniProt
 - P05091
 
抗原
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