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OGG1 抗体

This 兔 多克隆 anti-OGG1 antibody specifically detects OGG1 in WB, IHC, ELISA 和 IP. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN5700181
发货至: 中国
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for OGG1 抗体 (ABIN5700181)

抗原

See all OGG1 抗体
OGG1 (8-Oxoguanine DNA Glycosylase (OGG1))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This OGG1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)
  • 原理

    OGG1 antibody

    免疫原

    8-oxoguanine DNA glycosylase

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with FNab05980( OGG1 Antibody) at dilution of 1:600

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    OGG1 (8-Oxoguanine DNA Glycosylase (OGG1))

    别名

    OGG1

    背景

    Synonyms: N-glycosylase/DNA lyase|OGG1|MMH|MUTM|OGH1

    Background: This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined.

    分子量

    47 kDa

    基因ID

    4968

    UniProt

    O15527

    途径

    DNA Damage Repair
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