NEFL 抗体
Quick Overview for NEFL 抗体 (ABIN5699797)
抗原
See all NEFL 抗体适用
宿主
克隆类型
标记
应用范围
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免疫原
- neurofilament, light polypeptide
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亚型
- IgG
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应用备注
- WB : 1:1000-1:10000 IP :1:500-1:5000 IHC : 1:20-1:400 IF : 1:20-1:200
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说明
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mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab05710(NEFL antibody) at dilution of 1:4000
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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有效期
- 12 months
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- NEFL (Neurofilament, Light Polypeptide (NEFL))
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别名
- NF-L
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背景
- Synonyms:68 kDa neurofilament protein, CMT1F, CMT2E, FLJ53642, NEFL, NF L, NF68, NFL Background:Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y.
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分子量
- 65-68 kDa,140-160 kDa
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UniProt
- P07196
抗原
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