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ABAT 抗体

This anti-ABAT antibody is a 兔 多克隆 antibody detecting ABAT in WB, IHC, ELISA 和 IP. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN5699780
发货至: 中国

Quick Overview for ABAT 抗体 (ABIN5699780)

抗原

See all ABAT 抗体
ABAT (4-Aminobutyrate Aminotransferase (ABAT))

适用

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人, 小鼠, 大鼠

宿主

  • 45
  • 5

克隆类型

  • 43
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多克隆

标记

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This ABAT antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)
  • 免疫原

    4-aminobutyrate aminotransferase

    亚型

    IgG
  • 应用备注

    WB : 1:200-1:2000,IHC:1:20-1:200,IP:1:200-1:2000

    说明

    human liver tissue were subjected to SDS PAGE followed by western blot with FNab00026(ABAT antibody) at dilution of 1:300

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    有效期

    12 months
  • 抗原

    ABAT (4-Aminobutyrate Aminotransferase (ABAT))

    别名

    ABAT

    背景

    Synonyms:ABAT, FLJ17813, GABA aminotransferase, GABA AT, GABA T, GABA transaminase, GABAT, L AIBAT Background:4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95 % similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.

    分子量

    55kDa

    基因ID

    18

    UniProt

    P80404

    途径

    Monocarboxylic Acid Catabolic Process
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