VEGF 抗体
Quick Overview for VEGF 抗体 (ABIN5699617)
抗原
See all VEGF 抗体适用
宿主
克隆类型
标记
应用范围
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免疫原
- vascular endothelial growth factor A
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亚型
- IgG
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应用备注
- WB :1:200-1:2000,IP:1:200-1:2000,IF:1:10-1:100,IHC:1:50-1:500
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说明
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PC-3 cells were subjected to SDS PAGE followed by western blot with FNab09391(VEGFA antibody) at dilution of 1:800
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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有效期
- 12 months
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- VEGF (Vascular Endothelial Growth Factor (VEGF))
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别名
- VEGF
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背景
- Synonyms:L VEGFA, MVCD1, Vascular permeability factor, VEGF, VEGF A, VEGFA, VPF Background:VEGFA, also named as VEGF or VPF, belongs to the PDGF/VEGF growth factor family. It is a growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. VEGFA induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. It binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. Defects in VEGFA are a cause of susceptibility to microvascular complications of diabetes type 1(MVCD1). VEGFA has 13 isoforms with MW 16kd to 45kd. Some isoforms has homodimer form, such as VEGFA189(38kd), VEFGA110(34kd). VEGFA is a 34kd to 42kd, dimeric, disulfide-bound glycoprotein. VEGF-A exists in at least seven homodimeric isoforms. The monomers consist of 121, 145, 148, 165, 183, 189, or 206 amino acids(PMID:15602010).
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分子量
- 23-27kDa,45kDa
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UniProt
- P15692
抗原
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