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VEGFA 抗体 (AA 27-232)

This anti-VEGFA antibody is a 兔 多克隆 antibody detecting VEGFA in WB, IHC, ELISA, IP 和 IF. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN5699617
发货至: 中国

Quick Overview for VEGFA 抗体 (AA 27-232) (ABIN5699617)

抗原

See all VEGFA 抗体
VEGFA (Vascular Endothelial Growth Factor A (VEGFA))

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

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多克隆

标记

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This VEGFA antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF)
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    AA 27-232

    原理

    VEGFA antibody

    免疫原

    Immunogen sequence: 27-232aa

    Immunogen: vascular endothelial growth factor A

    亚型

    IgG
  • 应用备注

    WB :1:200-1:2000,IP:1:200-1:2000,IF:1:10-1:100,IHC:1:50-1:500

    说明

    PC-3 cells were subjected to SDS PAGE followed by western blot with FNab09391(VEGFA antibody) at dilution of 1:800

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    VEGFA (Vascular Endothelial Growth Factor A (VEGFA))

    别名

    VEGFA

    背景

    Synonyms: Vascular endothelial growth factor A, long form (L-VEGF)|Vascular permeability factor (VPF)|N-VEGF|VEGFA|VEGFA|VEGF

    Background: VEGFA, also named as VEGF or VPF, belongs to the PDGF/VEGF growth factor family. It is a growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. VEGFA induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. It binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. Defects in VEGFA are a cause of susceptibility to microvascular complications of diabetes type 1(MVCD1). VEGFA has 13 isoforms with MW 16kd to 45kd. Some isoforms has homodimer form, such as VEGFA189(38kd), VEFGA110(34kd). VEGFA is a 34kd to 42kd, dimeric, disulfide-bound glycoprotein. VEGF-A exists in at least seven homodimeric isoforms. The monomers consist of 121, 145, 148, 165, 183, 189, or 206 amino acids(PMID:15602010).

    分子量

    23-27kDa,45kDa

    UniProt

    P15692

    途径

    RTK signaling, Glycosaminoglycan Metabolic Process, Regulation of Cell Size, Tube Formation, Signaling Events mediated by VEGFR1 and VEGFR2, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling
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