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CDK4 抗体

This anti-CDK4 antibody is a 兔 多克隆 antibody detecting CDK4 in WB, ELISA, IHC, IP, IF 和 FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN5699229
发货至: 中国

Quick Overview for CDK4 抗体 (ABIN5699229)

抗原

See all CDK4 抗体
CDK4 (Cyclin-Dependent Kinase 4 (CDK4))

适用

  • 119
  • 69
  • 52
  • 19
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  • 1
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  • 1
人, 小鼠, 大鼠

宿主

  • 103
  • 36
  • 2
  • 1

克隆类型

  • 98
  • 43
多克隆

标记

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  • 10
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  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CDK4 antibody is un-conjugated

应用范围

  • 119
  • 48
  • 34
  • 33
  • 23
  • 22
  • 22
  • 14
  • 13
  • 11
  • 6
  • 4
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  • 1
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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), Flow Cytometry (FACS)
  • 免疫原

    cyclin-dependent kinase 4

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    HeLa cells were subjected to SDS PAGE followed by western blot with FNab01557(CDK4 antibody) at dilution of 1:1000

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    有效期

    12 months
  • 抗原

    CDK4 (Cyclin-Dependent Kinase 4 (CDK4))

    别名

    CDK4

    背景

    Synonyms:CDK4, Cell division protein kinase 4, CMM3, cyclin dependent kinase 4, PSK J3 Background:The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported.

    分子量

    34 kDa

    基因ID

    1019

    UniProt

    P11802

    途径

    Cell Division Cycle, Mitotic G1-G1/S Phases, Regulation of Cell Size
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