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GLUD1 抗体

This anti-GLUD1 antibody is a 兔 多克隆 antibody detecting GLUD1 in WB, IHC, IP 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN5697821
发货至: 中国

Quick Overview for GLUD1 抗体 (ABIN5697821)

抗原

See all GLUD1 抗体
GLUD1 (Glutamate Dehydrogenase 1 (GLUD1))

适用

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  • 2
  • 2
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  • 1
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  • 1
人, 小鼠, 大鼠

宿主

  • 47
  • 6
  • 1

克隆类型

  • 46
  • 8
多克隆

标记

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  • 5
  • 1
  • 1
  • 1
  • 1
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  • 1
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This GLUD1 antibody is un-conjugated

应用范围

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  • 6
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  • 1
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  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), ELISA
  • 免疫原

    glutamate dehydrogenase 1

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    HeLa cells were subjected to SDS PAGE followed by western blot with FNab03498(GLUD1 antibody) at dilution of 1:3000

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    有效期

    12 months
  • 抗原

    GLUD1 (Glutamate Dehydrogenase 1 (GLUD1))

    别名

    GLUD1

    背景

    Synonyms:GLUD Background:This gene encodes glutamate dehydrogenase, which is a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid-induced insulin secretion. It is allosterically activated by ADP and inhibited by GTP and ATP. Activating mutations in this gene are a common cause of congenital hyperinsulinism. Alternative splicing of this gene results in multiple transcript variants. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Related pseudogenes have been identified on chromosomes 10, 18 and X.

    分子量

    45-55 kDa

    基因ID

    2746

    UniProt

    P00367

    途径

    Positive Regulation of Peptide Hormone Secretion, Warburg Effect
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