GLUD1 抗体
Quick Overview for GLUD1 抗体 (ABIN5697821)
抗原
See all GLUD1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
免疫原
- glutamate dehydrogenase 1
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
说明
-
HeLa cells were subjected to SDS PAGE followed by western blot with FNab03498(GLUD1 antibody) at dilution of 1:3000
-
限制
- 仅限研究用
-
-
-
缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze / thaw cycles.
-
储存条件
- -20 °C
-
有效期
- 12 months
-
-
- GLUD1 (Glutamate Dehydrogenase 1 (GLUD1))
-
别名
- GLUD1
-
背景
- Synonyms:GLUD Background:This gene encodes glutamate dehydrogenase, which is a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid-induced insulin secretion. It is allosterically activated by ADP and inhibited by GTP and ATP. Activating mutations in this gene are a common cause of congenital hyperinsulinism. Alternative splicing of this gene results in multiple transcript variants. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Related pseudogenes have been identified on chromosomes 10, 18 and X.
-
分子量
- 45-55 kDa
-
基因ID
- 2746
-
UniProt
- P00367
-
途径
- Positive Regulation of Peptide Hormone Secretion, Warburg Effect
抗原
-