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FKBP8 抗体

This 兔 多克隆 antibody specifically detects FKBP8 in WB 和 ELISA. It exhibits reactivity toward 人 和 小鼠.
产品编号 ABIN5697691
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for FKBP8 抗体 (ABIN5697691)

抗原

See all FKBP8 抗体
FKBP8 (FK506 Binding Protein 8, 38kDa (FKBP8))

适用

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人, 小鼠

宿主

  • 67
  • 5
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克隆类型

  • 57
  • 15
多克隆

标记

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This FKBP8 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 原理

    FKBP8 antibody

    免疫原

    FK506 binding protein 8, 38kDa

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze / thaw cycles.

    储存条件

    -20 °C

    储存方法

    -20°C for 12 months

    有效期

    12 months
  • 抗原

    FKBP8 (FK506 Binding Protein 8, 38kDa (FKBP8))

    别名

    FKBP8

    背景

    Synonyms: Peptidyl-prolyl cis-trans isomerase FKBP8 (PPIase FKBP8)|38 kDa FK506-binding protein (38 kDa FKBP, FKBP-38, hFKBP38)|FK506-binding protein 8 (FKBP-8)|FKBPR38|Rotamase|FKBP8|FKBP38

    Background: Constitutively inactive PPiase, which becomes active when bound to calmodulin and calcium. Seems to act as a chaperone for BCL2, targets it to the mitochondria and modulates its phosphorylation state. The BCL2/FKBP8/calmodulin/calcium complex probably interferes with the binding of BCL2 to its targets. The active form of FKBP8 may therefore play a role in the regulation of apoptosis.

    分子量

    53 kDa

    基因ID

    23770

    UniProt

    Q14318

    途径

    Autophagy
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