alpha Actinin 抗体
This anti-alpha Actinin antibody is a 兔 多克隆 antibody detecting alpha Actinin in WB, IHC, ELISA 和 IF. Suitable for 人, 小鼠 和 大鼠.
Quick Overview for alpha Actinin 抗体 (ABIN5697056)
抗原
See all alpha Actinin (ACTN) 抗体
alpha Actinin (ACTN)
(alpha-Actinin Skeletal Muscle (ACTN))
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This alpha Actinin antibody is un-conjugated
应用范围
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
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免疫原
- actinin, alpha 1
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亚型
- IgG
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anti-alpha-Actinin Skeletal Muscle (ACTN) antibody
ACTN 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB : 1:1000-1:10000 IHC : 1:50-1:500 IF : 1:50-1:500
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说明
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NIH/3T3 cells were subjected to SDS PAGE followed by western blot with FNab00322( a-Actinin Antibody) at dilution of 1:2000
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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有效期
- 12 months
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- alpha Actinin (ACTN) (alpha-Actinin Skeletal Muscle (ACTN))
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别名
- alpha Actinin
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背景
- Synonyms:actinin, alpha 1, ACTN1, alpha Actinin, Alpha actinin 1, F actin cross linking protein, Non muscle alpha actinin 1 Background:Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene.
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分子量
- 103 kDa
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UniProt
- P12814
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途径
- Cell-Cell Junction Organization, Negative Regulation of Transporter Activity
抗原
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