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PROX1 抗体 (C-Term)

This anti-PROX1 antibody is a 兔 多克隆 antibody detecting PROX1 in WB, IHC (p) 和 IHC (fro). Suitable for 人, 小鼠, 大鼠 和 鱼.
产品编号 ABIN569679
发货至: 中国
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Quick Overview for PROX1 抗体 (C-Term) (ABIN569679)

抗原

See all PROX1 抗体
PROX1 (Prospero Homeobox 1 (PROX1))

适用

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人, 小鼠, 大鼠, 鱼

宿主

  • 94
  • 7

克隆类型

  • 92
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多克隆

标记

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This PROX1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 16
    • 12
    • 9
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    C-Term

    特异性

    This antibody is reactive with Prox-1. It will be a useful tool to study lymphatic vessel density in and around human tumors. It will detect Prox-1 in the nucleus of lymphatic endothelial cells.

    纯化方法

    Purified

    免疫原

    Peptide corresponding to the Homeobox domain of Prox1.
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C/-80 °C

    储存方法

    Store lyophilized (preferably in a desiccator) at -20 °C and in aliquots at -80 °C. Reconstituted antibody can be stored at 4 °C for a limited period of time, it does not show decline in activity after two weeks at 4 °C.
  • 抗原

    PROX1 (Prospero Homeobox 1 (PROX1))

    别名

    PROX-1

    背景

    The homeobox gene Prox-1 was originally cloned by homology to the Drosophila melanogaster gene prospero. Prox-1 is expressed in a subpopulation of endothelial cells which by budding and sprouting, give rise to the lymphatic system. Prox-1-deficient homozygous mice have unaffected vasculogenesis and angiogenesis, but liver and lymphatics do not develop. Human Prox-1 gene has been mapped to chromosome 1q32.2-q32.3, and its product shows 94 % similarity to the chicken protein. The conserved structure and expression pattern of the Prox-1 gene imply that it may play the same roles in humans as in other vertebrates. The human Prox-1 gene is most actively expressed in the developing lens. Anti-Prox-1 antibodies provide a highly specific marker of lymphatic endothelial cells.Synonyms: Homeobox prospero-like protein PROX1, PROX1, Prospero homeobox protein 1

    基因ID

    5629

    NCBI登录号

    NP_002754

    UniProt

    Q92786

    途径

    Stem Cell Maintenance, Regulation of Muscle Cell Differentiation
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