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Isocitrate Dehydrogenase 抗体 (Internal Region)

The 山羊 多克隆 anti-Isocitrate Dehydrogenase antibody (ABIN569649) specifically detects Isocitrate Dehydrogenase in WB 和 EIA. The antibody is reactive with 人, 大鼠, 小鼠, 犬, 绵羊 和 Cow samples.
产品编号 ABIN569649
发货至: 中国
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Quick Overview for Isocitrate Dehydrogenase 抗体 (Internal Region) (ABIN569649)

抗原

See all Isocitrate Dehydrogenase (IDH) 抗体
Isocitrate Dehydrogenase (IDH)

适用

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人, 大鼠, 小鼠, 犬, 绵羊, Cow

宿主

  • 14
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山羊

克隆类型

  • 15
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多克隆

标记

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This Isocitrate Dehydrogenase antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

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    AA 65-77, Internal Region

    序列

    KKHNVGVKCA TIT

    特异性

    Recognizes IDH1 (65-77).

    交叉反应 (详细)

    Species reactivity (expected):Canine (Dog), Sheep.
    Species reactivity (tested):Human, Mouse, Rat.

    纯化方法

    Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide

    免疫原

    Peptide with sequence from the internal region of the protein sequence according to NP_005887.2.
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Tris saline, pH ~7.3 with 0.02 % Sodium Azide and 0.5 % BSA

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    Isocitrate Dehydrogenase (IDH)

    别名

    Isocitrate Dehydrogenase / IDH

    背景

    IDH1 belongs to two distinct subclasses. The protein is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. This protein contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production.Synonyms: Cytosolic NADP-isocitrate dehydrogenase, ICDH, IDP, NADP(+)-specific ICDH, Oxalosuccinate decarboxylase, PICD, cytoplasmic Isocitrate dehydrogenase [NADP]

    分子量

    46.7kDa (NP_005887.2).

    基因ID

    3417

    NCBI登录号

    NP_005887

    UniProt

    O75874
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