DCTN3 抗体 (Internal Region)
Quick Overview for DCTN3 抗体 (Internal Region) (ABIN569634)
抗原
See all DCTN3 (Dctn3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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序列
- C-QVALGNISSK RE
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特异性
- This antibody is expected to recognize both reported isoforms (NP_009165.1, NP_077324.1).
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交叉反应 （详细）
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Species reactivity (expected):Canine (Dog), Bovine.
Species reactivity (tested):Human, Mouse, Rat. -
纯化方法
- Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide
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免疫原
- Peptide with sequence from the internal region of the protein sequence according to NP_009165.1 and NP_077324.1. Genename: DCTN3
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anti-Dynactin 3 (p22) (Dctn3) (Internal Region) antibody
Verified Dctn3 适用: 人, 大鼠 ELISA, IHC, WB, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Dynactin 3 (p22) (Dctn3) (AA 1-176) antibodyDctn3 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Dynactin 3 (p22) (Dctn3) (AA 41-150) antibodyDctn3 适用: 大鼠, 小鼠 ELISA, WB, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Dynactin 3 (p22) (Dctn3) (AA 2-176) antibodyDctn3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dynactin 3 (p22) (Dctn3) antibodyDctn3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dynactin 3 (p22) (Dctn3) (N-Term) antibodyDctn3 适用: 人, 大鼠 ELISA, IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Dynactin 3 (p22) (Dctn3) (AA 1-176) antibodyDctn3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dynactin 3 (p22) (Dctn3) (C-Term) antibodyDctn3 适用: 人, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, pH ~7.3 with 0.02 % Sodium Azide and 0.5 % BSA
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- DCTN3 (Dctn3) (Dynactin 3 (p22) (Dctn3))
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别名
- Dynactin Subunit 3
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背景
- This gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like most other dynactin subunits, exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin. Alternative splicing of this gene generates 2 transcript variants. Transcript Variant: This variant contains an additional 97 nt within the 3' coding region, as compared to variant 1 resulting in a frame-shift. Isoform 2 encoded by this variant has a different, and 10 aa shorter C-terminus than isoform 1.Synonyms: DCTN22, DCTN3
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分子量
- 19.5kDa (NP_077324.1).
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基因ID
- 11258
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NCBI登录号
- NP_009165
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UniProt
- O75935
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途径
- M Phase
抗原
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