SFRP1 抗体 (C-Term)
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Quick Overview for SFRP1 抗体 (C-Term) (ABIN569588)
抗原
See all SFRP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- KNHECPTFQS VFK
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特异性
- Recognizes Secreted Frizzled-related Protein 1 (SFRP1) at C-term.
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交叉反应 (详细)
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Species reactivity (expected):Bovine and Mouse.
Species reactivity (tested):Human. -
纯化方法
- Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
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免疫原
- Synthetic peptide corresponding to the C-terminus of Human SFRP1 (NP_003003.3).
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- SFRP1 (Secreted Frizzled-Related Protein 1 (SFRP1))
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别名
- SFRP1
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背景
- SFRP1 (also known as FRP, FRP1, SARP2, Secreted Apoptosis-related Protein 2, Secreted Frizzled-related Protein and Secreted frizzled-related protein 1) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. SFRP1 and SFRP5 may be involved in determining the polarity of photoreceptor cells in the retina. SFRP1 is expressed in several human tissues, with the highest levels in heart.Synonyms: FRP, FRP-1, FRP1, SARP-2, SARP2, SFRP-1, Secreted apoptosis-related protein 2, Secreted frizzled-related protein 1
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基因ID
- 6422
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NCBI登录号
- NP_003003
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UniProt
- Q8N474
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途径
- WNT signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Negative Regulation of Hormone Secretion, Regulation of Intracellular Steroid Hormone Receptor Signaling, Stem Cell Maintenance, Tube Formation, Positive Regulation of fat Cell Differentiation
抗原
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