RPGR 抗体 (AA 13-338)
Quick Overview for RPGR 抗体 (AA 13-338) (ABIN5693297)
抗原
See all RPGR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 13-338
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原理
- Anti-RPGR Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-RPGR Antibody Picoband® (ABIN5693297). Tested in ELISA, WB applications. This antibody reacts with Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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免疫原
- E. coli-derived human RPGR recombinant protein (Position: A13-F338).
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亚型
- IgG
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anti-Retinitis Pigmentosa GTPase Regulator (RPGR) (AA 1-260) antibody
RPGR 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Retinitis Pigmentosa GTPase Regulator (RPGR) (AA 1-180) antibodyRPGR 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Retinitis Pigmentosa GTPase Regulator (RPGR) (C-Term) antibodyRPGR 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Retinitis Pigmentosa GTPase Regulator (RPGR) (AA 744-772) antibodyRPGR 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB31028 unconjugated
anti-Retinitis Pigmentosa GTPase Regulator (RPGR) (AA 743-772), (C-Term) antibodyRPGR 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
ELISA, 0.1-0.5 μg/mL
1. "Entrez Gene: RPGR retinitis pigmentosa GTPase regulator". 2. Murga-Zamalloa CA, Atkins SJ, Peranen J, Swaroop A, Khanna H (Sep 2010). "Interaction of retinitis pigmentosa GTPase regulator (RPGR) with RAB8A GTPase: implications for cilia dysfunction and photoreceptor degeneration". Human Molecular Genetics. 19 (18): 3591-8. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- RPGR (Retinitis Pigmentosa GTPase Regulator (RPGR))
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别名
- RPGR
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背景
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Synonyms: X-linked retinitis pigmentosa GTPase regulator, RPGR, RP3, XLRP3
Tissue Specificity: Heart, brain, placenta, lung, liver, muscle, kidney, retina, pancreas and fetal retinal pigment epithelium. Isoform 3 is found only in the retina. Colocalizes with RPGRIP1 in the outer segment of rod photoreceptors and cone outer segments.
Background: X-linked retinitis pigmentosa GTPase regulator is a GTPase-binding protein that in humans is encoded by the RPGR gene. This gene encodes a protein with a series of six RCC1-like domains (RLDs), characteristic of the highly conserved guanine nucleotide exchange factors. The encoded protein is found in the Golgi body and interacts with RPGRIP1. This protein localizes to the outer segment of rod photoreceptors and is essential for their viability. Mutations in this gene have been associated with X-linked retinitis pigmentosa (XLRP). Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length natures of only some have been determined.
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分子量
- 113 kDa
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基因ID
- 6103
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UniProt
- Q92834
抗原
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