IL36A/IL1F6 抗体 (AA 6-151)
Quick Overview for IL36A/IL1F6 抗体 (AA 6-151) (ABIN5693268)
抗原
See all IL36A/IL1F6 (IL1F6) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 6-151
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原理
- Anti-IL36 alpha/IL36A Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-IL36 alpha/IL36A Antibody Picoband® (ABIN5693268). Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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免疫原
- E. coli-derived human IL36 alpha recombinant protein (Position: K6-D151).
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亚型
- IgG
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anti-Interleukin 1 Family, Member 6 (IL1F6) antibody
IL1F6 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Family, Member 6 (IL1F6) (AA 35-61) antibodyIL1F6 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB25982 unconjugated
anti-Interleukin 1 Family, Member 6 (IL1F6) (AA 1-158) antibodyIL1F6 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Family, Member 6 (IL1F6) antibodyIL1F6 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Family, Member 6 (IL1F6) (AA 1-158) antibodyIL1F6 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Interleukin 1 Family, Member 6 (IL1F6) (AA 1-158) antibodyIL1F6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 1 Family, Member 6 (IL1F6) (AA 6-151) antibodyIL1F6 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
ELISA (Cap), 1-5 μg/mL
1. Smith DE, Renshaw BR, Ketchem RR, Kubin M, Garka KE, Sims JE (Feb 2000). "Four new members expand the interleukin-1 superfamily". J Biol Chem. 275 (2): 1169-75. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- IL36A/IL1F6 (IL1F6) (Interleukin 1 Family, Member 6 (IL1F6))
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别名
- IL36A
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背景
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Synonyms: Interleukin-36 alpha, FIL1 epsilon, Interleukin-1 epsilon, IL-1 epsilon, Interleukin-1 family member 6, IL-1F6, IL36A, FIL1E, IL1E, IL1F6
Tissue Specificity: Expressed in immune system and fetal brain, but not in other tissues tested or in multiple hematopoietic cell lines. Predominantly expressed in skin keratinocytes but not in fibroblasts, endothelial cells or melanocytes. Increased in lesional psoriasis skin.
Background: Interleukin-36 alpha also known as interleukin-1 family member 6 (IL1F6) is a protein that in humans is encoded by the IL36A gene. The protein encoded by this gene is a cytokine that can activate NF-kappa-B and MAPK signaling pathways to generate an inflammatory response. The encoded protein functions primarily in skin and demonstrates increased expression in psoriasis. In addition, decreased expression of this gene has been linked to a poor prognosis in both hepatocellular carcinoma and colorectal cancer patients.
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分子量
- 25 kDa
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基因ID
- 27179
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途径
- Cancer Immune Checkpoints
抗原
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