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MUC2 抗体

The 兔 多克隆 anti-MUC2 antibody is suitable to detect MUC2 in samples from 人, 小鼠 和 大鼠. It has been validated for IHC 和 IF.
产品编号 ABIN5693242
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for MUC2 抗体 (ABIN5693242)

抗原

See all MUC2 抗体
MUC2 (Mucin 2, Oligomeric Mucus/gel-Forming (MUC2))

适用

  • 95
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人, 小鼠, 大鼠

宿主

  • 81
  • 32

克隆类型

  • 63
  • 50
多克隆

标记

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  • 3
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  • 1
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This MUC2 antibody is un-conjugated

应用范围

  • 71
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  • 10
  • 4
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Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 原理

    Anti-MUC2 Antibody

    序列

    DDFKTASGLV EATGAGFANT WKAQSTCHDK LDWLDD

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Antibody (ABIN5693242). Tested in IF, IHC applications. This antibody reacts with Human, Mouse, Rat.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human MUC2, which shares 86.1% amino acid (aa) sequence identity with both mouse and rat MUC2.

    亚型

    IgG
  • 应用备注

    Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
    Immunofluorescence, 5 μg/mL, Human, Mouse

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    MUC2 (Mucin 2, Oligomeric Mucus/gel-Forming (MUC2))

    别名

    MUC2

    背景

    Synonyms: Mucin-2, MUC-2, Intestinal mucin-2, MUC2, SMUC

    Tissue Specificity: Colon, small intestine, colonic tumors, bronchus, cervix and gall bladder.

    Background: Mucin 2, also known as MUC2, is a protein that in humans is encoded by the MUC2 gene. This gene encodes a member of the mucin protein family. It is mapped to 11p15.5. Mucin 2 is particularly prominent in the gut where it is secreted from goblet cells in the epithelial lining into the lumen of the large intestine. There, mucin 2, along with small amounts of related-mucin proteins, polymerizes into a gel of which 80 % by weight is oligosaccharide side-chains that are added as post-translational modifications to the mucin proteins. This gel provides an insoluble mucous barrier that serves to protect the intestinal epithelium. The primary function of the MUC2 gene product is to provide a protective barrier between the epithelial surfaces and the gut lumen. There is decreased expression of MUC2 in colonic cancer and defective polymerization of secreted mucin in ulcerative colitis.

    分子量

    38 kDa

    基因ID

    4583

    UniProt

    Q02817
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