MUC2 抗体
Quick Overview for MUC2 抗体 (ABIN5693242)
抗原
See all MUC2 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Anti-MUC2 Antibody
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序列
- DDFKTASGLV EATGAGFANT WKAQSTCHDK LDWLDD
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-MUC2 Antibody Picoband® (ABIN5693242). Tested in IF, IHC applications. This antibody reacts with Human, Mouse, Rat.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human MUC2, which shares 86.1% amino acid (aa) sequence identity with both mouse and rat MUC2.
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亚型
- IgG
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anti-Mucin 2, Oligomeric Mucus/gel-Forming (MUC2) (C-Term) antibody
MUC2 适用: 人 IHC, WB, IF, ICC, IHC (p), IHC (fro), FISH 宿主: 兔 Polyclonal unconjugated
anti-Mucin 2, Oligomeric Mucus/gel-Forming (MUC2) (AA 27-110) antibodyMUC2 适用: 小鼠 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Mucin 2, Oligomeric Mucus/gel-Forming (MUC2) (AA 4850-4950) antibodyMUC2 适用: 人 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Mucin 2, Oligomeric Mucus/gel-Forming (MUC2) (AA 4373-4557) antibodyMUC2 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 7B8G10 unconjugated
anti-Mucin 2, Oligomeric Mucus/gel-Forming (MUC2) antibodyMUC2 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal MLP-842 unconjugated
anti-Mucin 2, Oligomeric Mucus/gel-Forming (MUC2) antibodyMUC2 适用: 人, 小鼠, 大鼠 IHC, WB, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mucin 2, Oligomeric Mucus/gel-Forming (MUC2) (AA 4373-4557) antibodyMUC2 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 2G4B7 unconjugated
anti-Mucin 2, Oligomeric Mucus/gel-Forming (MUC2) (AA 569-657) antibodyMUC2 适用: 人 IHC, WB, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Mucin 2, Oligomeric Mucus/gel-Forming (MUC2) (AA 36-351) antibodyMUC2 适用: Pig IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Mucin 2, Oligomeric Mucus/gel-Forming (MUC2) antibodyMUC2 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
Immunofluorescence, 5 μg/mL, Human, Mouse
1. Allen, A., Hutton, D. A., Pearson, J. P. The MUC2 gene product: a human intestinal mucin. Int. J. Biochem. Cell Biol. 30: 797-801, 1998. 2. Rousseau K, Byrne C, Kim YS, Gum JR, Swallow DM, Toribara NW (May 2004). "The complete genomic organization of the human MUC6 and MUC2 mucin genes". Genomics 83 (5): 936-9. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- MUC2 (Mucin 2, Oligomeric Mucus/gel-Forming (MUC2))
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别名
- MUC2
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背景
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Synonyms: Mucin-2, MUC-2, Intestinal mucin-2, MUC2, SMUC
Tissue Specificity: Colon, small intestine, colonic tumors, bronchus, cervix and gall bladder.
Background: Mucin 2, also known as MUC2, is a protein that in humans is encoded by the MUC2 gene. This gene encodes a member of the mucin protein family. It is mapped to 11p15.5. Mucin 2 is particularly prominent in the gut where it is secreted from goblet cells in the epithelial lining into the lumen of the large intestine. There, mucin 2, along with small amounts of related-mucin proteins, polymerizes into a gel of which 80 % by weight is oligosaccharide side-chains that are added as post-translational modifications to the mucin proteins. This gel provides an insoluble mucous barrier that serves to protect the intestinal epithelium. The primary function of the MUC2 gene product is to provide a protective barrier between the epithelial surfaces and the gut lumen. There is decreased expression of MUC2 in colonic cancer and defective polymerization of secreted mucin in ulcerative colitis.
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分子量
- 38 kDa
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基因ID
- 4583
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UniProt
- Q02817
抗原
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