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KDM2A 抗体

KDM2A 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5693222
发货至: 中国
  • 抗原 See all KDM2A 抗体
    KDM2A (Lysine (K)-Specific Demethylase 2A (KDM2A))
    适用
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    人, 小鼠, 大鼠
    宿主
    • 40
    • 2
    • 1
    克隆类型
    • 42
    • 1
    多克隆
    标记
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    This KDM2A antibody is un-conjugated
    应用范围
    • 18
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    Western Blotting (WB)
    品牌
    Picoband™
    序列
    KRTFDLEEKL HTNKYNANFV TFMEGKDFNV EYIQR
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for FBXL11 detection. Tested with WB in Human,Mouse,Rat.
    免疫原
    A synthetic peptide corresponding to a sequence of human FBXL11 (KRTFDLEEKLHTNKYNANFVTFMEGKDFNVEYIQR).
    Top Product
    Discover our top product KDM2A Primary Antibody
  • 应用备注

    Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

    Application Details: Western blot, 0.1-0.5 μg/mL

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    缓冲液
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    KDM2A (Lysine (K)-Specific Demethylase 2A (KDM2A))
    别名
    KDM2A (KDM2A 产品)
    别名
    FBXL11 antibody, JHDM1A antibody, 100043628 antibody, 5530401A10Rik antibody, AA589516 antibody, AW536790 antibody, Cxxc8 antibody, Fbl11 antibody, Fbl7 antibody, Fbxl11 antibody, Gm4560 antibody, Jhdm1 antibody, Jhdm1a antibody, lalina antibody, KDM2A antibody, CXXC8 antibody, FBL11 antibody, FBL7 antibody, LILINA antibody, fb76b11 antibody, wu:fb76b11 antibody, wu:fj11c04 antibody, zgc:158441 antibody, zgc:158606 antibody, lysine demethylase 2A antibody, lysine (K)-specific demethylase 2A antibody, lysine (K)-specific demethylase 2Aa antibody, KDM2A antibody, Kdm2a antibody, kdm2aa antibody
    背景

    Synonyms: Lysine-specific demethylase 2A, CXXC-type zinc finger protein 8, F-box and leucine-rich repeat protein 11, F-box protein FBL7, F-box protein Lilina, F-box/LRR-repeat protein 11, JmjC domain-containing histone demethylation protein 1A, [Histone-H3]-lysine-36 demethylase 1A, KDM2A, CXXC8, FBL7, FBXL11, JHDM1A, KIAA1004

    Tissue Specificity: Widely expressed, with highest levels in brain, testis and ovary, followed by lung.

    Background: Lysine-specific demethylase 2A (KDM2A) also known as F-box and leucine-rich repeat protein 11 (FBXL11) is an enzyme that in humans is encoded by the KDM2A gene. This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least six highly degenerated leucine-rich repeats. This family member plays a role in epigenetic silencing. It nucleates at CpG islands and specifically demethylates both mono- and di-methylated lysine-36 of histone H3. Alternative splicing results in multiple transcript variants.

    UniProt
    Q9Y2K7
    途径
    Warburg Effect
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