KDM2A 抗体
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北京 101111
Quick Overview for KDM2A 抗体 (ABIN5693222)
抗原
See all KDM2A 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Anti-FBXL11/KDM2A Antibody
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序列
- KRTFDLEEKL HTNKYNANFV TFMEGKDFNV EYIQR
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-FBXL11/KDM2A Antibody (ABIN5693222). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human FBXL11, which shares 97.1% and 100% amino acid (aa) sequence identity with mouse and rat FBXL11, respectively.
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亚型
- IgG
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anti-Lysine (K)-Specific Demethylase 2A (KDM2A) antibody
KD Validated KDM2A 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB160 unconjugated Recombinant Antibody
anti-Lysine (K)-Specific Demethylase 2A (KDM2A) (AA 1-150) antibodyKDM2A 适用: 人 ELISA 宿主: 小鼠 Monoclonal 5C11F7 unconjugated
anti-Lysine (K)-Specific Demethylase 2A (KDM2A) antibodyKDM2A 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 2A (KDM2A) (N-Term) antibodyKDM2A 适用: 人, 小鼠, 大鼠, 犬, 马, 兔, Cow, Pig, 豚鼠, 斑马鱼, Bat, 猴, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 2A (KDM2A) (N-Term) antibodyKDM2A 适用: 人, 小鼠, 大鼠, 犬, Pig, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 2A (KDM2A) (AA 500-527) antibodyKDM2A 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB14392 unconjugated
anti-Lysine (K)-Specific Demethylase 2A (KDM2A) antibodyKDM2A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 2A (KDM2A) (AA 445-459) antibodyVerified KDM2A 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 2A (KDM2A) (AA 1-782) antibodyKDM2A 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 2A (KDM2A) (N-Term) antibodyKDM2A 适用: 人, 小鼠, 大鼠, 犬, 马, 兔, Cow, 豚鼠, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- KDM2A (Lysine (K)-Specific Demethylase 2A (KDM2A))
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别名
- KDM2A
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背景
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Synonyms: Lysine-specific demethylase 2A, CXXC-type zinc finger protein 8, F-box and leucine-rich repeat protein 11, F-box protein FBL7, F-box protein Lilina, F-box/LRR-repeat protein 11, JmjC domain-containing histone demethylation protein 1A, [Histone-H3]-lysine-36 demethylase 1A, KDM2A, CXXC8, FBL7, FBXL11, JHDM1A, KIAA1004
Tissue Specificity: Widely expressed, with highest levels in brain, testis and ovary, followed by lung.
Background: Lysine-specific demethylase 2A (KDM2A) also known as F-box and leucine-rich repeat protein 11 (FBXL11) is an enzyme that in humans is encoded by the KDM2A gene. This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least six highly degenerated leucine-rich repeats. This family member plays a role in epigenetic silencing. It nucleates at CpG islands and specifically demethylates both mono- and di-methylated lysine-36 of histone H3. Alternative splicing results in multiple transcript variants.
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分子量
- 150 kDa
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基因ID
- 22992
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UniProt
- Q9Y2K7
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途径
- Warburg Effect
抗原
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