KDM2A 抗体
Quick Overview for KDM2A 抗体 (ABIN5693222)
抗原
See all KDM2A 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Anti-FBXL11/KDM2A Antibody Picoband®
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序列
- KRTFDLEEKL HTNKYNANFV TFMEGKDFNV EYIQR
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-FBXL11/KDM2A Antibody Picoband® (ABIN5693222). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human FBXL11, which shares 97.1% and 100% amino acid (aa) sequence identity with mouse and rat FBXL11, respectively.
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亚型
- IgG
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anti-Lysine (K)-Specific Demethylase 2A (KDM2A) (AA 1-150) antibody
KDM2A 适用: 人 ELISA 宿主: 小鼠 Monoclonal 5C11F7 unconjugated
anti-Lysine (K)-Specific Demethylase 2A (KDM2A) antibodyKDM2A 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 2A (KDM2A) (N-Term) antibodyKDM2A 适用: 人, 小鼠, 大鼠, 犬, 马, 兔, Cow, Pig, 豚鼠, 斑马鱼, Bat, 猴, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 2A (KDM2A) (N-Term) antibodyKDM2A 适用: 人, 小鼠, 大鼠, 犬, Pig, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 2A (KDM2A) (AA 500-527) antibodyKDM2A 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB14392 unconjugated
anti-Lysine (K)-Specific Demethylase 2A (KDM2A) (AA 445-459) antibodyVerified KDM2A 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 2A (KDM2A) (AA 1-782) antibodyKDM2A 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 2A (KDM2A) antibodyKDM2A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 2A (KDM2A) (N-Term) antibodyKDM2A 适用: 人, 小鼠, 大鼠, 犬, 马, 兔, Cow, 豚鼠, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 2A (KDM2A) antibodyKDM2A 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
1. "Entrez Gene: FBXL11 F-box and leucine-rich repeat protein 11". 2. Nagase T, Ishikawa K, Suyama M, Kikuno R, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Jul 1999). "Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 6 (1): 63-70. 3. Winston JT, Koepp DM, Zhu C, Elledge SJ, Harper JW (Dec 1999). "A family of mammalian F-box proteins".Curr Biol. 9 (20): 1180-2. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- KDM2A (Lysine (K)-Specific Demethylase 2A (KDM2A))
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别名
- KDM2A
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背景
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Synonyms: Lysine-specific demethylase 2A, CXXC-type zinc finger protein 8, F-box and leucine-rich repeat protein 11, F-box protein FBL7, F-box protein Lilina, F-box/LRR-repeat protein 11, JmjC domain-containing histone demethylation protein 1A, [Histone-H3]-lysine-36 demethylase 1A, KDM2A, CXXC8, FBL7, FBXL11, JHDM1A, KIAA1004
Tissue Specificity: Widely expressed, with highest levels in brain, testis and ovary, followed by lung.
Background: Lysine-specific demethylase 2A (KDM2A) also known as F-box and leucine-rich repeat protein 11 (FBXL11) is an enzyme that in humans is encoded by the KDM2A gene. This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least six highly degenerated leucine-rich repeats. This family member plays a role in epigenetic silencing. It nucleates at CpG islands and specifically demethylates both mono- and di-methylated lysine-36 of histone H3. Alternative splicing results in multiple transcript variants.
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分子量
- 150 kDa
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基因ID
- 22992
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UniProt
- Q9Y2K7
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途径
- Warburg Effect
抗原
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