CDC45 抗体 (AA 166-431)
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- 抗原 See all CDC45 抗体
- CDC45 (Cell Division Cycle 45 Homolog (S. Cerevisiae) (CDC45))
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抗原表位
- AA 166-431
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CDC45 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 品牌
- Picoband™
- 交叉反应 (详细)
- No cross reactivity with other proteins.
- 产品特性
- Rabbit IgG polyclonal antibody for CDC45L detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.
- 免疫原
- E. coli-derived human CDC45L recombinant protein (Position: E166-A431).
- Top Product
- Discover our top product CDC45 Primary Antibody
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- 应用备注
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Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.
Application Details: Western blot, 0.1-0.5 μg/mL
Direct ELISA, 0.1-0.5 μg/mL - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- CDC45 (Cell Division Cycle 45 Homolog (S. Cerevisiae) (CDC45))
- 别名
- CDC45 (CDC45 产品)
- 背景
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Synonyms: Cell division control protein 45 homolog, PORC-PI-1, CDC45, CDC45L, CDC45L2, UNQ374/PRO710
Tissue Specificity: Widely expressed, highest levels are found in adult testis and thymus and in fetal liver.
Background: CDC45 is a protein that in humans is encoded by the CDC45L gene. The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Alternate splicing results in multiple transcript variants.
- UniProt
- O75419
- 途径
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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