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CD5 抗体 (DyLight 488)

This anti-CD5 antibody is a 兔 多克隆 antibody detecting CD5 in FACS. Suitable for 人.
产品编号 ABIN7354524
发货至: 中国

Quick Overview for CD5 抗体 (DyLight 488) (ABIN7354524)

抗原

See all CD5 抗体
CD5

适用

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宿主

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克隆类型

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多克隆

标记

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This CD5 antibody is conjugated to DyLight 488

应用范围

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Flow Cytometry (FACS)
  • 原理

    Anti-Human CD5 DyLight® 488 conjugated Antibody

    序列

    KKLVKKFRQK KQRQWIGPTG MNQNMSFHRN HTATVRSH

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-Human CD5 DyLight® 488 conjugated Antibody -Dyl488. Tested in Flow Cytometry applications. This antibody reacts with Human.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human CD5, which shares 92.1% and 89.5% amino acid (aa) sequence identity with mouse and rat CD5, respectively.

    亚型

    IgG
  • 应用备注

    Flow Cytometry (Fixed), 1-3 μg/1x106 cells1. Lundell, A.-C., Johansen, S., Adlerberth, I., Wold, A. E., Hesselmar, B., Rudin, A. High proportion of CD5+ B cells in infants predicts development of allergic disease. J. Immun. 193: 510-518, 2014. 2. Zhang, C., Xin, H., Zhang, W., Yazaki, P. J., Zhang, Z., Le, K., Li, W., Lee, H., Kwak, L., Forman, S., Jove, R., Yu, H. CD5 binds to interleukin-6 and induces a feed-forward loop with the transcription factor STAT3 in B cells to promote cancer. Immunity 44: 913-923, 2016.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
  • 抗原

    CD5

    别名

    CD5

    背景

    Synonyms: T-cell surface glycoprotein CD5, Lymphocyte antigen T1/Leu-1, CD5, CD5, LEU1

    Background: CD5 is a member of the scavenger receptor cysteine-rich (SRCR) superfamily. Members of this family are secreted or membrane-anchored proteins mainly found in cells associated with the immune system. In humans, the gene is located on the long arm of chromosome 11. This protein is a type-I transmembrane glycoprotein found on the surface of thymocytes, T lymphocytes and a subset of B lymphocytes. The encoded protein contains three SRCR domains and may act as a receptor to regulate T-cell proliferation. Alternative splicing results in multiple transcript variants encoding different isoforms.

    分子量

    39 kDa

    基因ID

    921

    UniProt

    P06127
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