CD1c 抗体 (AA 73-287)
Quick Overview for CD1c 抗体 (AA 73-287) (ABIN5693174)
抗原
See all CD1c (CD1C) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 73-287
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原理
- Anti-CD1c Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-CD1c Antibody Picoband® (ABIN5693174). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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免疫原
- E. coli-derived human CD1c recombinant protein (Position: K73-L287).
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亚型
- IgG
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应用备注
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Western blot, 0.1-0.5 μg/mL
1. Granelli-Piperno, A., Shimeliovich, I., Pack, M., Trumpfheller, C., Steinman, R. M. HIV-1 selectively infects a subset of nonmaturing BDCA1-positive dendritic cells in human blood. J. Immun. 176: 991-998, 2006. 2. Moody, D. B., Ulrichs, T., Muhlecker, W., Young, D. C., Gurcha, S. S., Grant, E., Rosat, J.-P., Brenner, M. B., Costello, C. E., Besra, G. S., Porcelli, S. A. CD1c-mediated T-cell recognition of isoprenoid glycolipids in Mycobacterium tuberculosis infection. Nature 404: 884-888, 2000. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- CD1c (CD1C) (T-cell surface glycoprotein CD1c (CD1C))
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别名
- CD1C
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背景
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Synonyms: T-cell surface glycoprotein CD1c, CD1c, CD1C
Tissue Specificity: Expressed on cortical thymocytes, on certain T-cell leukemias, and in various other tissues.
Background: CD1C is a group-1 member of the CD1 family of major histocompatibility (MHC)-like glycoproteins. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known.
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分子量
- 62 kDa
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基因ID
- 911
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UniProt
- P29017
抗原
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