Glutathione Reductase 抗体 (AA 256-522)
Quick Overview for Glutathione Reductase 抗体 (AA 256-522) (ABIN5693151)
抗原
See all Glutathione Reductase (GSR) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 256-522
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原理
- Anti-Glutathione Reductase/GSR Antibody Picoband®
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交叉反应 (详细)
- No cross reactivity with other proteins.
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产品特性
- Anti-Glutathione Reductase/GSR Antibody Picoband® (ABIN5693151). Tested in ELISA, Flow Cytometry, IF, IHC-P, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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免疫原
- E. coli-derived human Glutathione Reductase recombinant protein (Position: K256-R522).
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亚型
- IgG
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应用备注
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Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL
Immunocytochemistry/Immunofluorescence, 5 μg/mL
Flow Cytometry(Fixed), 1-3 μg/1x106 cells
ELISA, 0.1-0.5 μg/mL
1. Deponte M (May 2013). "Glutathione catalysis and the reaction mechanisms of glutathione-dependent enzymes". Biochim. Biophys. Acta. 1830 (5): 3217-66. 2. Meister A (November 1988). "Glutathione metabolism and its selective modification". J. Biol. Chem. 263 (33): 17205-8. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- Glutathione Reductase (GSR)
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别名
- GSR
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背景
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Synonyms: Glutathione reductase, mitochondrial, GR, GRase, GSR, GLUR, GRD1
Tissue Specificity: Expressed in peripheral blood leukocytes.
Background: Glutathione reductase (GR), also known as glutathione-disulfide reductase (GSR), is an enzyme that in humans is encoded by the GSR gene. This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found.
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分子量
- 52 kDa
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基因ID
- 2936
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UniProt
- P00390
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途径
- Thyroid Hormone Synthesis, Cell RedoxHomeostasis
抗原
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