GNS 抗体 (AA 238-355)
Quick Overview for GNS 抗体 (AA 238-355) (ABIN5693115)
抗原
See all GNS 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 238-355
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原理
- Anti-GNS Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-GNS Antibody Picoband® (ABIN5693115). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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免疫原
- E. coli-derived human GNS recombinant protein (Position: W238-R355).
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亚型
- IgG
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anti-Glucosamine (N-Acetyl)-6-Sulfatase (GNS) (AA 293-552) antibody
GNS 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glucosamine (N-Acetyl)-6-Sulfatase (GNS) (AA 1-552) antibodyGNS 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Glucosamine (N-Acetyl)-6-Sulfatase (GNS) (AA 293-552) antibodyGNS 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glucosamine (N-Acetyl)-6-Sulfatase (GNS) (AA 283-313) antibodyGNS 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB19341 unconjugated
anti-Glucosamine (N-Acetyl)-6-Sulfatase (GNS) (C-Term) antibodyGNS 适用: 人, 小鼠, 大鼠, Cow, 山羊, 豚鼠, 马, 兔, 犬, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glucosamine (N-Acetyl)-6-Sulfatase (GNS) antibodyGNS 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Glucosamine (N-Acetyl)-6-Sulfatase (GNS) (AA 1-552) antibodyGNS 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Glucosamine (N-Acetyl)-6-Sulfatase (GNS) (AA 312-361) antibodyGNS 适用: 人, 小鼠, 大鼠, Cow, 山羊, 豚鼠, 马, 兔, 犬, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Glucosamine (N-Acetyl)-6-Sulfatase (GNS) (AA 398-447) antibodyGNS 适用: 人, 小鼠, 大鼠, Cow, 山羊, 豚鼠, 马, 兔, 斑马鱼, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Glucosamine (N-Acetyl)-6-Sulfatase (GNS) (C-Term) antibodyGNS 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
ELISA, 0.1-0.5 μg/mL
1. "Entrez Gene: Glucosamine (N-acetyl)-6-sulfatase". 2. Basner R, Kresse H, von Figura K (February 1979). "N-Acetylglucosamine-6-sulfate sulfatase from human urine". J. Biol. Chem. 254 (4): 1151-8. 3. Kresse H, Fuchs W, Glössl J, Holtfrerich D, Gilberg W (December 1981). "N-acetylglucosamine-6-sulfate by human β-N-acetylhexosaminidase A". J. Biol. Chem. 256 (24): 12926-32. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- GNS (Glucosamine (N-Acetyl)-6-Sulfatase (GNS))
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别名
- GNS
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背景
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Synonyms: N-acetylglucosamine-6-sulfatase, Glucosamine-6-sulfatase, G6S, GNS
Tissue Specificity: Found only in peripheral nervous system Schwann cells.
Background: N-acetylglucosamine-6-sulfatase, also known as glucosamine (N-acetyl)-6-sulfatase, is an enzyme that in humans is encoded by the GNS gene. The product of this gene is a lysosomal enzyme found in all cells. It is involved in the catabolism of heparin, heparan sulphate, and keratan sulphate. Deficiency of this enzyme results in the accumulation of undegraded substrate and the lysosomal storage disorder mucopolysaccharidosis type IIID (Sanfilippo D syndrome). Mucopolysaccharidosis type IIID is the least common of the four subtypes of Sanfilippo syndrome.
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分子量
- 90 kDa
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基因ID
- 2799
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UniProt
- P15586
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途径
- Glycosaminoglycan Metabolic Process
抗原
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