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GNS 抗体 (AA 238-355)

This anti-GNS antibody is a 兔 多克隆 antibody detecting GNS in WB 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN5693115
发货至: 中国

Quick Overview for GNS 抗体 (AA 238-355) (ABIN5693115)

抗原

See all GNS 抗体
GNS (Glucosamine (N-Acetyl)-6-Sulfatase (GNS))

适用

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人, 小鼠, 大鼠

宿主

  • 29
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克隆类型

  • 32
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多克隆

标记

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This GNS antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 238-355

    原理

    Anti-GNS Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-GNS Antibody Picoband® (ABIN5693115). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    免疫原

    E. coli-derived human GNS recombinant protein (Position: W238-R355).

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL
    ELISA, 0.1-0.5 μg/mL
    1. "Entrez Gene: Glucosamine (N-acetyl)-6-sulfatase". 2. Basner R, Kresse H, von Figura K (February 1979). "N-Acetylglucosamine-6-sulfate sulfatase from human urine". J. Biol. Chem. 254 (4): 1151-8. 3. Kresse H, Fuchs W, Glössl J, Holtfrerich D, Gilberg W (December 1981). "N-acetylglucosamine-6-sulfate by human β-N-acetylhexosaminidase A". J. Biol. Chem. 256 (24): 12926-32.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    GNS (Glucosamine (N-Acetyl)-6-Sulfatase (GNS))

    别名

    GNS

    背景

    Synonyms: N-acetylglucosamine-6-sulfatase, Glucosamine-6-sulfatase, G6S, GNS

    Tissue Specificity: Found only in peripheral nervous system Schwann cells.

    Background: N-acetylglucosamine-6-sulfatase, also known as glucosamine (N-acetyl)-6-sulfatase, is an enzyme that in humans is encoded by the GNS gene. The product of this gene is a lysosomal enzyme found in all cells. It is involved in the catabolism of heparin, heparan sulphate, and keratan sulphate. Deficiency of this enzyme results in the accumulation of undegraded substrate and the lysosomal storage disorder mucopolysaccharidosis type IIID (Sanfilippo D syndrome). Mucopolysaccharidosis type IIID is the least common of the four subtypes of Sanfilippo syndrome.

    分子量

    90 kDa

    基因ID

    2799

    UniProt

    P15586

    途径

    Glycosaminoglycan Metabolic Process
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