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DNMT1 抗体 (AA 22-126)

Name: DNMT1 抗体 (AA 22-126)
SKU: ABIN5693103
Availability: OutOfStock

DNMT1 适用: 人 WB, ELISA, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated

Western blot analysis of Dnmt1 using anti-Dnmt1 antibody . (DNMT1 抗体 (AA 22-126))

IHC analysis of Dnmt1 using anti-Dnmt1 antibody . (DNMT1 抗体 (AA 22-126))

IHC

5 images

产品编号 ABIN5693103

发货至: 中国

Datasheet as PDF

抗原 See all DNMT1 抗体

DNMT1 (DNA (Cytosine-5)-Methyltransferase 1 (DNMT1))
抗原表位
21

20

12

11

10

10

9

8

7

5

4

4

3

3

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1
AA 22-126
适用
166

37

28

3

2

1

1

1

1

1

1
人
宿主
135

33

1
兔
Compatible Secondaries
克隆类型
121

48
多克隆
标记
72

13

12

10

8

8

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2
This DNMT1 antibody is un-conjugated
应用范围
104

67

42

36

28

27

20

13

13

13

9

4

4

3

3

1

1

1

1

1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

原理

Anti-Dnmt1 Antibody Picoband®

交叉反应（详细）

No cross-reactivity with other proteins.

产品特性

Anti-Dnmt1 Antibody Picoband® (ABIN5693103). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

免疫原

E. coli-derived human Dnmt1 recombinant protein (Position: D22-N126).

亚型

IgG

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DNMT1 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated

anti-DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) antibody
DNMT1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) antibody
KO Validated DNMT1 适用: 人 WB, IHC, IP, IF, ChIP 宿主: 兔 Monoclonal unconjugated

anti-DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) (AA 1448-1594) antibody
DNMT1 适用: 人, 猴 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 7C11A2 unconjugated

anti-DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) (AA 21-120) antibody
DNMT1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) (AA 1-270) antibody
DNMT1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) (AA 1317-1616) antibody
DNMT1 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 2D10G8 unconjugated

anti-DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) (AA 881-914) antibody
DNMT1 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB51461 unconjugated

anti-DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) (AA 1317-1616) antibody
DNMT1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D5G2 unconjugated

anti-DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) (AA 767-912) antibody
DNMT1 适用: 人 IHC, ISt, StM 宿主: 小鼠 Monoclonal DNMT1-2061 unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL
Immunocytochemistry/Immunofluorescence, 5 μg/mL
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells
ELISA, 0.1-0.5 μg/mL
1. Bigey, P., Ramchandani, S., Theberge, J., Araujo, F. D., Szyf, M. Transcriptional regulation of the human DNA methyltransferase (dnmt1) gene. Gene 242: 407-418, 2000. 2. Chen, T., Hevi, S., Gay, F., Tsujimoto, N., He, T., Zhang, B., Ueda, Y., Li, E. Complete activation of DNMT1 leads to mitotic catastrophe in human cancer cells. Nature Genet. 39: 391-396, 2007.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
抗原

DNMT1 (DNA (Cytosine-5)-Methyltransferase 1 (DNMT1))

别名

DNMT1 (DNMT1 产品)

背景

Synonyms: DNA (cytosine-5)-methyltransferase 1, Dnmt1, CXXC-type zinc finger protein 9, DNA methyltransferase HsaI, DNA MTase HsaI, M.HsaI, MCMT, DNMT1, AIM, CXXC9, DNMT
Tissue Specificity: Ubiquitous, highly expressed in fetal tissues, heart, kidney, placenta, peripheral blood mononuclear cells, and expressed at lower levels in spleen, lung, brain, small intestine, colon, liver, and skeletal muscle. Isoform 2 is less expressed than isoform 1.
Background: DNA (cytosine-5)-methyltransferase 1 is an enzyme that in humans is encoded by the DNMT1 gene. This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants.

分子量

200 kDa

基因ID

1786

UniProt

P26358

途径

SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection