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IGF2R 抗体 (AA 424-529)

Name: IGF2R 抗体 (AA 424-529)
SKU: ABIN5693085
Availability: OutOfStock

IGF2R 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, FACS, IF, ICC 宿主: 兔 Polyclonal unconjugated

Western blot analysis of IGF2R using anti-IGF2R antibody . (IGF2R 抗体 (AA 424-529))

IHC analysis of IGF2R using anti-IGF2R antibody . (IGF2R 抗体 (AA 424-529))

IHC

5 images

(1 reference)

产品编号 ABIN5693085

发货至: 中国

Datasheet as PDF

抗原 See all IGF2R 抗体

IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))
抗原表位
15

11

6

4

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 424-529
适用
73

24

8

8

3

2

1

1

1
人, 小鼠, 大鼠
宿主
52

22
兔
Compatible Secondaries
克隆类型
50

24
多克隆
标记
41

5

4

4

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This IGF2R antibody is un-conjugated
应用范围
33

31

23

15

13

12

12

10

7

6

3

2

2

1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Immunocytochemistry (ICC)

原理

Anti-Mannose 6 Phosphate Receptor (Cation independent)/IGF2R Antibody Picoband®

交叉反应（详细）

No cross-reactivity with other proteins.

产品特性

Anti-Mannose 6 Phosphate Receptor (Cation independent)/IGF2R Antibody Picoband® (ABIN5693085). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

免疫原

E. coli-derived human IGF2R recombinant protein (Position: F424-R529).

亚型

IgG
anti-Insulin-Like Growth Factor 2 Receptor (IGF2R) (AA 2327-2491) antibody
IGF2R 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Insulin-Like Growth Factor 2 Receptor (IGF2R) antibody
IGF2R 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated

anti-Insulin-Like Growth Factor 2 Receptor (IGF2R) (AA 160-311) antibody
IGF2R 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 4F1G1 unconjugated

anti-Insulin-Like Growth Factor 2 Receptor (IGF2R) (AA 2475-2491), (C-Term) antibody
IGF2R 适用: 人, 小鼠, 大鼠 WB, FACS 宿主: 兔 Polyclonal unconjugated

anti-Insulin-Like Growth Factor 2 Receptor (IGF2R) (AA 2201-2400) antibody
IGF2R 适用: 人 ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Insulin-Like Growth Factor 2 Receptor (IGF2R) (AA 2167-2442) antibody
IGF2R 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Insulin-Like Growth Factor 2 Receptor (IGF2R) (AA 2328-2491) antibody
IGF2R 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Insulin-Like Growth Factor 2 Receptor (IGF2R) (pSer2409) antibody
IGF2R 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Insulin-Like Growth Factor 2 Receptor (IGF2R) (pSer2409) antibody
IGF2R 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Insulin-Like Growth Factor 2 Receptor (IGF2R) antibody (Biotin)
IGF2R 适用: 人, Non-Human Primate WB, FACS, IP 宿主: 小鼠 Monoclonal MEM-238 Biotin

应用备注

Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL
Immunocytochemistry/Immunofluorescence, 5 μg/mL
Flow Cytometry(Fixed), 1-3 μg/1x10⁶ cells
ELISA, 0.1-0.5 μg/mL
1. Killian, J. K., Oka, Y., Jang, H.-S., Fu, X., Waterland, R. A., Sohda, T., Sakaguchi, S., Jirtle, R. L. Mannose 6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) variants in American and Japanese populations. Hum. Mutat. 18: 25-31, 2001. 2. Latos, P. A., Pauler, F. M., Koerner, M. V., Senergin, H. B., Hudson, Q. J., Stocsits, R. R., Allhoff, W., Stricker, S. H., Klement, R. M., Warczok, K. E., Aumayr, K., Pasierbek, P., Barlow, D. P. Airn transcriptional overlap, but not its IncRNA products, induces imprinted Igf2r silencing. Science 338: 1469-1472, 2012.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Liang, Hao, Zhang, Wu, Wang: "Insulin-like growth factors in endometrioid adenocarcinoma: correlation with clinico-pathological features and estrogen receptor expression." in: BMC cancer, Vol. 12, pp. 262, (2013) (PubMed).
抗原

IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))

别名

IGF2R (IGF2R 产品)

背景

Synonyms: Cation-independent mannose-6-phosphate receptor, CI Man-6-P receptor, CI-MPR, M6PR, 300 kDa mannose 6-phosphate receptor, MPR 300, Insulin-like growth factor 2 receptor, Insulin-like growth factor II receptor, IGF-II receptor, M6P/IGF2 receptor, M6P/IGF2R, CD222, IGF2R, MPRI
Tissue Specificity: Liver.
Background: Insulin-like growth factor 2 receptor, also called IGF2R or I-MPR is a protein that in humans is encoded by the IGF2R gene. This gene is mapped to 6q25.3. This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate, although the binding sites for either are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. While the related mouse gene shows exclusive expression from the maternal allele, imprinting of the human gene appears to be polymorphic, with only a minority of individuals showing expression from the maternal allele.

分子量

274 kDa

基因ID

3482

UniProt

P11717