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CD163 抗体 (AA 47-201)

Cited in 2+ publications. This 兔 多克隆 anti-CD163 antibody specifically detects CD163 in WB, IHC 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN5693082
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD163 抗体 (AA 47-201) (ABIN5693082)

抗原

See all CD163 抗体
CD163

适用

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宿主

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多克隆

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This CD163 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
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    AA 47-201

    原理

    Anti-CD163 Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti- Antibody (ABIN5693082). Tested in ELISA, IHC, WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived human CD163 recombinant protein (Position: T47-E201).

    亚型

    IgG
  • 应用备注

    Western blot, 0.25-0.5 μg/mL
    Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL
    ELISA, 0.1-0.5 μg/mL

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Liu, Xiao, Liu, Li, Zhou, Xian, Wang, Zhang, Wang, Ho, Zhuang: "SIV Infection Impairs the Central Nervous System in Chinese Rhesus Macaques." in: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, Vol. 11, Issue 3, pp. 592-600, (2017) (PubMed).

    Huang, Chen, Wang, Wang, Ning, He, Hu, Yuan, Li, Wang, Liu, Chen, Ren, Sun: "Detecting cell-in-cell structures in human tumor samples by E-cadherin/CD68/CD45 triple staining." in: Oncotarget, Vol. 6, Issue 24, pp. 20278-87, (2016) (PubMed).

  • 抗原

    CD163

    别名

    CD163

    背景

    Synonyms: Scavenger receptor cysteine-rich type 1 protein M130, Hemoglobin scavenger receptor, CD163, Soluble CD163, sCD163, CD163, M130

    Tissue Specificity: Expressed in monocytes and mature macrophages such as Kupffer cells in the liver, red pulp macrophages in the spleen, cortical macrophages in the thymus, resident bone marrow macrophages and meningeal macrophages of the central nervous system. Expressed also in blood. Isoform 1 is the lowest abundant in the blood. Isoform 2 is the lowest abundant in the liver and the spleen. Isoform 3 is the predominant isoform detected in the blood.

    Background: CD163 (Cluster of Differentiation 163) is a protein that in humans is encoded by the CD163 gene. The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

    分子量

    150 kDa

    基因ID

    9332
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