PRKAB2 抗体 (N-Term)
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北京 101111
Quick Overview for PRKAB2 抗体 (N-Term) (ABIN5693058)
抗原
See all PRKAB2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- N-Term
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原理
- Anti-AMPK beta 2 PRKAB2 Antibody (monoclonal, 6G1)
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序列
- DKEFVSWQQD LEDSVKPTQQ ARPTVIRWSE GGKE
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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预测反应
- different from the related mouse sequence by three amino acids,and from the related rat sequence by two amino acids.
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产品特性
- Anti-AMPK beta 2 PRKAB2 Antibody.(monoclonal, 6G1). Tested in Flow Cytometry, IHC, ICC, WB applications. This antibody reacts with Human.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human AMPK beta 2, different from the related mouse sequence by three amino acids, and from the related rat sequence by two amino acids.
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亚型
- IgG2b
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anti-Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2) (AA 1-120) antibody
PRKAB2 适用: 人 IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 8F5B2 unconjugated
anti-Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2) (N-Term) antibodyPRKAB2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2) (AA 1-120) antibodyPRKAB2 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 7A8C3 unconjugated
anti-Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2) (AA 1-272) antibodyPRKAB2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2G9 unconjugated
anti-Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2) (AA 1-272) antibodyPRKAB2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2) (AA 1-110) antibodyPRKAB2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2) (AA 1-272) antibodyPRKAB2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2) (AA 3-33), (N-Term) antibodyPRKAB2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB3183 unconjugated
anti-Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2) (N-Term) antibodyPRKAB2 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2) (AA 1-272) antibodyPRKAB2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, 0.1-0.5 μg/mL Immunohistochemistry (Frozen Section), 0.5-1 μg/mL Immunocytochemistry, 0.5-1 μg/mL Flow Cytometry (Fixed), 1-3 μg/1x106 cells
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- PRKAB2 (Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2))
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别名
- PRKAB2
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背景
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Background: 5'-AMP-activated protein kinase subunit beta-2 is an enzyme that in humans is encoded by the PRKAB2 gene. The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. It is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Multiple alternatively spliced transcript variants have been found for this gene.
Gene Full Name: protein kinase AMP-activated non-catalytic subunit beta 2
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分子量
- 34 kDa
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基因ID
- 5565
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UniProt
- O43741
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途径
- AMPK Signaling, Warburg Effect
抗原
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