电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

EPO 抗体 (AA 34-192)

This anti-EPO antibody is a 兔 多克隆 antibody detecting EPO in WB. Suitable for 小鼠 和 大鼠.
产品编号 ABIN5693048
发货至: 中国

Quick Overview for EPO 抗体 (AA 34-192) (ABIN5693048)

抗原

See all EPO 抗体
EPO (Erythropoietin (EPO))

适用

  • 166
  • 32
  • 26
  • 7
  • 7
  • 6
  • 6
  • 4
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
小鼠, 大鼠

宿主

  • 132
  • 82
  • 2
  • 1
  • 1

克隆类型

  • 124
  • 94
多克隆

标记

  • 128
  • 18
  • 12
  • 7
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This EPO antibody is un-conjugated

应用范围

  • 146
  • 107
  • 69
  • 44
  • 42
  • 42
  • 32
  • 22
  • 13
  • 13
  • 11
  • 8
  • 8
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 48
    • 21
    • 16
    • 11
    • 11
    • 6
    • 6
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 34-192

    原理

    Anti-EPO Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-EPO Antibody Picoband® (ABIN5693048). Tested in WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    免疫原

    E. coli-derived mouse EPO recombinant protein (Position: D34-R192).

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL
    1. Hosseini-Zare MS, Dashti-Khavidaki S, Mahdavi-Mazdeh M, Ahmadi F, Akrami S (2012). "Peripheral neuropathy response to erythropoietin in type 2 diabetic patients with mild to moderate renal failure". Clinical Neurology and Neurosurgery. 114 (6): 663-7. 2. Middleton SA, Barbone FP, Johnson DL, Thurmond RL, You Y, McMahon FJ, Jin R, Livnah O, Tullai J, Farrell FX, Goldsmith MA, Wilson IA, Jolliffe LK (1999). "Shared and unique determinants of the erythropoietin (EPO) receptor are important for binding EPO and EPO mimetic peptide". The Journal of Biological Chemistry. 274 (20): 14163-9.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    EPO (Erythropoietin (EPO))

    别名

    Epo

    物质类

    Hormone

    背景

    Synonyms: Erythropoietin, Epo

    Tissue Specificity: Produced by kidney or liver of adult mammals and by liver of fetal or neonatal mammals.

    Background: This EPO gene encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. The encoded protein is mainly synthesized in the kidney, secreted into the blood plasma, and binds to the erythropoietin receptor to promote red blood cell production, or erythropoiesis, in the bone marrow. Expression of this gene is upregulated under hypoxic conditions, in turn leading to increased erythropoiesis and enhanced oxygen-carrying capacity of the blood. Expression of this gene has also been observed in brain and in the eye, and elevated expression levels have been observed in diabetic retinopathy and ocular hypertension. Recombinant forms of the encoded protein exhibit neuroprotective activity against a variety of potential brain injuries, as well as antiapoptotic functions in several tissue types, and have been used in the treatment of anemia and to enhance the efficacy of cancer therapies.

    分子量

    28 kDa

    基因ID

    13856

    UniProt

    P07321

    途径

    JAK/STAT Signaling, Hormone Activity, Negative Regulation of intrinsic apoptotic Signaling, Negative Regulation of Transporter Activity
You are here:
Chat with us!