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PARN 抗体 (AA 1-301)

Name: PARN 抗体 (AA 1-301)
SKU: ABIN5693032
Availability: OutOfStock

PARN 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC, FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated

Western blot analysis of PARN using anti-PARN antibody . (PARN 抗体 (AA 1-301))

IHC analysis of PARN using anti-PARN antibody . (PARN 抗体 (AA 1-301))

IHC

4 images

产品编号 ABIN5693032

发货至: 中国

Datasheet as PDF

抗原 See all PARN 抗体

PARN (Poly A Specific Ribonuclease (PARN))
抗原表位
7

4

4

2

1

1

1

1

1

1

1
AA 1-301
适用
37

8

6

3

3

3

2

2

2

2

1

1

1
人, 小鼠, 大鼠
宿主
28

9
兔
Compatible Secondaries
克隆类型
31

6
多克隆
标记
25

2

2

2

1

1

1

1

1

1
This PARN antibody is un-conjugated
应用范围
27

11

11

9

4

1

1

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

原理

Anti-PARN Antibody Picoband®

交叉反应（详细）

No cross-reactivity with other proteins.

产品特性

Anti-PARN Antibody Picoband® (ABIN5693032). Tested in ELISA, Flow Cytometry, IF, IHC, IHC-F, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

免疫原

E. coli-derived human PARN recombinant protein (Position: M1-Y301).

亚型

IgG

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PARN 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

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PARN 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Poly A Specific Ribonuclease (PARN) antibody
PARN 适用: 人, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Poly A Specific Ribonuclease (PARN) (AA 501-599) antibody
PARN 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated

anti-Poly A Specific Ribonuclease (PARN) antibody
PARN 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Poly A Specific Ribonuclease (PARN) (AA 1-280) antibody
PARN 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Poly A Specific Ribonuclease (PARN) antibody
PARN 适用: 人 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated

anti-Poly A Specific Ribonuclease (PARN) antibody
PARN 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Poly A Specific Ribonuclease (PARN) (C-Term) antibody
PARN 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Poly A Specific Ribonuclease (PARN) (N-Term) antibody
PARN 适用: 人, 小鼠, 大鼠, Cow, 犬, 猴, 豚鼠, 马, 兔, Bat, 小鸡 WB 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
Immunohistochemistry (Frozen Section), 0.5-1 μg/mL
Immunocytochemistry/Immunofluorescence, 2 μg/mL
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells
ELISA, 0.1-0.5 μg/mL
1. "Entrez Gene: PARN poly(A)-specific ribonuclease (deadenylation nuclease)". 2. Buiting K, Korner C, Ulrich B, Wahle E, Horsthemke B (May 2000). "The human gene for the poly(A)-specific ribonuclease (PARN) maps to 16p13 and has a truncated copy in the Prader-Willi/Angelman syndrome region on 15q11→q13". Cytogenet Cell Genet. 87 (1-2): 125-31.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
抗原

PARN (Poly A Specific Ribonuclease (PARN))

别名

PARN (PARN 产品)

背景

Synonyms: Poly (A)-specific ribonuclease PARN, Deadenylating nuclease, Deadenylation nuclease, Polyadenylate-specific ribonuclease, PARN, DAN
Tissue Specificity: Ubiquitous.
Background: Poly (A)-specific ribonuclease (PARN), also known as polyadenylate-specific ribonuclease or deadenylating nuclease (DAN), is an enzyme that in humans is encoded by the PARN gene. The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly (A) as the substrate, hence, efficiently degrades poly (A) tails of mRNAs. Exonucleolytic degradation of the poly (A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons.

分子量

78 kDa

基因ID

5073

UniProt

O95453