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ICOS 抗体 (AA 21-200)

This 兔 多克隆 anti-ICOS antibody specifically detects ICOS in WB, IHC 和 ELISA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN5693001
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for ICOS 抗体 (AA 21-200) (ABIN5693001)

抗原

See all ICOS 抗体
ICOS (Inducible T-Cell Co-Stimulator (ICOS))

适用

  • 106
  • 39
  • 33
  • 5
人, 小鼠, 大鼠

宿主

  • 87
  • 17
  • 12
  • 4
  • 2
  • 1

克隆类型

  • 71
  • 51
  • 1
多克隆

标记

  • 52
  • 16
  • 8
  • 8
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ICOS antibody is un-conjugated

应用范围

  • 72
  • 37
  • 34
  • 31
  • 21
  • 16
  • 13
  • 13
  • 10
  • 9
  • 7
  • 6
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

    • 15
    • 9
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-200

    原理

    Anti-ICOS Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-ICOS Antibody (ABIN5693001). Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    免疫原

    E. coli-derived mouse ICOS recombinant protein (Position: E21-S200).

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
    ELISA, 0.1-0.5 μg/mL

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    ICOS (Inducible T-Cell Co-Stimulator (ICOS))

    别名

    Icos

    背景

    Synonyms: Inducible T-cell costimulator, Activation-inducible lymphocyte immunomediatory molecule, CD28 and CTLA-4-like protein, CCLP, CD28-related protein 1, CRP-1, CD278, Icos, Ailim

    Tissue Specificity: Expressed on activated T-cells and resting memory T-cells. High expression seen in the thymic medulla and in the germinal centers and T-cell zones of lymph nodes and Peyer patches. Expressed at low levels in the spleen.

    Background: Inducible T-cell costimulator is an immune checkpoint protein that in humans is encoded by the ICOS gene. The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation.

    分子量

    20 kDa

    基因ID

    54167

    途径

    Cancer Immune Checkpoints
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