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ICOS 抗体 (AA 21-200)

Name: ICOS 抗体 (AA 21-200)
SKU: ABIN5693001
Availability: OutOfStock

ICOS 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

Western blot analysis of ICOS using anti-ICOS antibody . (ICOS 抗体 (AA 21-200))

IHC analysis of ICOS using anti-ICOS antibody . (ICOS 抗体 (AA 21-200))

IHC

4 images

产品编号 ABIN5693001

发货至: 中国

Datasheet as PDF

抗原 See all ICOS 抗体

ICOS (Inducible T-Cell Co-Stimulator (ICOS))
抗原表位
15

9

6

5

5

4

3

2

2

1

1

1

1

1

1

1
AA 21-200
适用
90

31

26

5
人, 小鼠, 大鼠
宿主
83

19

4

2

1

1
兔
Compatible Secondaries
克隆类型
77

32

1
多克隆
标记
51

17

7

6

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This ICOS antibody is un-conjugated
应用范围
71

41

31

30

19

15

14

13

9

8

7

6

4

2

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA

原理

Anti-ICOS Antibody Picoband®

交叉反应（详细）

No cross-reactivity with other proteins.

产品特性

Anti-ICOS Antibody Picoband® (ABIN5693001). Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

免疫原

E. coli-derived mouse ICOS recombinant protein (Position: E21-S200).

亚型

IgG

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anti-Inducible T-Cell Co-Stimulator (ICOS) (AA 21-140) antibody
ICOS 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Inducible T-Cell Co-Stimulator (ICOS) (AA 156-185) antibody
ICOS 适用: 人 WB, IHC, FACS, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Inducible T-Cell Co-Stimulator (ICOS) antibody
ICOS 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated

anti-Inducible T-Cell Co-Stimulator (ICOS) (Internal Region) antibody
Verified ICOS 适用: 人 IHC, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-Inducible T-Cell Co-Stimulator (ICOS) (AA 1-199) antibody
ICOS 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Inducible T-Cell Co-Stimulator (ICOS) antibody
ICOS 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Inducible T-Cell Co-Stimulator (ICOS) (AA 21-140) antibody
ICOS 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3G4 unconjugated

anti-Inducible T-Cell Co-Stimulator (ICOS) antibody
ICOS 适用: 人 IHC, FACS, IP, IHC (fro) 宿主: 小鼠 Monoclonal ISA-3 unconjugated

anti-Inducible T-Cell Co-Stimulator (ICOS) (AA 39-133) antibody
ICOS 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Inducible T-Cell Co-Stimulator (ICOS) (AA 156-185), (C-Term) antibody
ICOS 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB2237 unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
ELISA, 0.1-0.5 μg/mL
1. Hutloff A, Dittrich AM, Beier KC, Eljaschewitsch B, Kraft R, Anagnostopoulos I, Kroczek RA (Jan 1999). "ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28". Nature. 397(6716): 263-6. 2. Rudd CE, Schneider H (Jul 2003). "Unifying concepts in CD28, ICOS and CTLA4 co-receptor signalling". Nature Reviews. Immunology. 3 (7): 544-56.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
抗原

ICOS (Inducible T-Cell Co-Stimulator (ICOS))

别名

Icos (ICOS 产品)

背景

Synonyms: Inducible T-cell costimulator, Activation-inducible lymphocyte immunomediatory molecule, CD28 and CTLA-4-like protein, CCLP, CD28-related protein 1, CRP-1, CD278, Icos, Ailim
Tissue Specificity: Expressed on activated T-cells and resting memory T-cells. High expression seen in the thymic medulla and in the germinal centers and T-cell zones of lymph nodes and Peyer patches. Expressed at low levels in the spleen.
Background: Inducible T-cell costimulator is an immune checkpoint protein that in humans is encoded by the ICOS gene. The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation.

分子量

20 kDa

基因ID

54167

途径

Cancer Immune Checkpoints