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ICOS 抗体 (AA 21-140) (DyLight 488)

This anti-ICOS antibody is a 兔多克隆 antibody detecting ICOS in FACS. Suitable for 人.

产品编号 ABIN7354492

发货至: 中国

Quick Overview for ICOS 抗体 (AA 21-140) (DyLight 488) (ABIN7354492)

抗原

See all ICOS 抗体

ICOS (Inducible T-Cell Co-Stimulator (ICOS))

适用

人

宿主

84
19
4
2
1
1
1
1

兔

克隆类型

多克隆

标记

53
17
8
6
4
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1

This ICOS antibody is conjugated to DyLight 488

应用范围

72
42
32
32
19
15
14
13
9
8
7
6
4
2
1
1
1
1
1

Flow Cytometry (FACS)

Discover our top product ICOS Primary Antibody

抗原表位
15

9

5

5

5

4

3

2

2

1

1

1

1

1

1

1

1
AA 21-140

原理

Anti-Human ICOS DyLight® 488 conjugated Antibody

交叉反应（详细）

No cross-reactivity with other proteins.

产品特性

Anti-Human ICOS DyLight® 488 conjugated Antibody -Dyl488. Tested in Flow Cytometry applications. This antibody reacts with Human.

免疫原

E. coli-derived human ICOS recombinant protein (Position: E21-K140).

亚型

IgG
anti-Inducible T-Cell Co-Stimulator (ICOS) (AA 21-140) antibody
ICOS 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Inducible T-Cell Co-Stimulator (ICOS) (AA 156-185) antibody
ICOS 适用: 人 WB, IHC, FACS, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Inducible T-Cell Co-Stimulator (ICOS) (Internal Region) antibody
Verified ICOS 适用: 人 IHC, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-Inducible T-Cell Co-Stimulator (ICOS) antibody
ICOS 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated

anti-Inducible T-Cell Co-Stimulator (ICOS) (AA 21-200) antibody
ICOS 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Inducible T-Cell Co-Stimulator (ICOS) (AA 1-199) antibody
ICOS 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Inducible T-Cell Co-Stimulator (ICOS) antibody
ICOS 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Inducible T-Cell Co-Stimulator (ICOS) (AA 21-140) antibody
ICOS 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3G4 unconjugated

anti-Inducible T-Cell Co-Stimulator (ICOS) antibody
ICOS 适用: 人 IHC, FACS, IP, IHC (fro) 宿主: 小鼠 Monoclonal ISA-3 unconjugated

anti-Inducible T-Cell Co-Stimulator (ICOS) (AA 39-133) antibody
ICOS 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells1. Hutloff A, Dittrich AM, Beier KC, Eljaschewitsch B, Kraft R, Anagnostopoulos I, Kroczek RA (Jan 1999). "ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28". Nature. 397(6716): 263-6. 2. Rudd CE, Schneider H (Jul 2003). "Unifying concepts in CD28, ICOS and CTLA4 co-receptor signalling". Nature Reviews. Immunology. 3 (7): 544-56.

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
抗原

ICOS (Inducible T-Cell Co-Stimulator (ICOS))

别名

ICOS

背景

Synonyms: Inducible T-cell costimulator, Activation-inducible lymphocyte immunomediatory molecule, CD278, ICOS, AILIM
Tissue Specificity: Activated T-cells. Highly expressed on tonsillar T-cells, which are closely associated with B-cells in the apical light zone of germinal centers, the site of terminal B- cell maturation. Expressed at lower levels in thymus, lung, lymph node and peripheral blood leukocytes. Expressed in the medulla of fetal and newborn thymus.
Background: Inducible T-cell costimulator is an immune checkpoint protein that in humans is encoded by the ICOS gene. The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation.

分子量

39 kDa

基因ID

29851

UniProt

Q9Y6W8

途径

Cancer Immune Checkpoints

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