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ICAM1 抗体 (AA 28-268)

This anti-ICAM1 antibody is a 兔 多克隆 antibody detecting ICAM1 in WB, FACS, IHC, ELISA, IF 和 ICC. Suitable for 人, 小鼠 和 大鼠. This Primary Antibody has been cited in 18+ publications.
Pubmed (18 references)
产品编号 ABIN5692991
发货至: 中国

Quick Overview for ICAM1 抗体 (AA 28-268) (ABIN5692991)

抗原

See all ICAM1 抗体
ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))

适用

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人, 小鼠, 大鼠

宿主

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  • 22
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兔

克隆类型

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  • 107
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多克隆

标记

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This ICAM1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
Discover our top product ICAM1 Primary Antibody

  • 抗原表位

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    AA 28-268

    原理

    Anti-ICAM1 Antibody Picoband®

    交叉反应 （详细）

    No cross-reactivity with other proteins.

    产品特性

    Anti-ICAM1 Antibody Picoband® (ABIN5692991). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    免疫原

    E. coli-derived human ICAM1 recombinant protein (Position: Q28-R268).

    亚型

    IgG
  • anti-Intercellular Adhesion Molecule 1 (ICAM1) (AA 201-300) antibody
    anti-Intercellular Adhesion Molecule 1 (ICAM1) (AA 201-300) antibody

    ICAM1 适用: 人, 小鼠, 大鼠, 兔 WB, FACS, ELISA, ICC, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated

    anti-Intercellular Adhesion Molecule 1 (ICAM1) (AA 198-537) antibody
    anti-Intercellular Adhesion Molecule 1 (ICAM1) (AA 198-537) antibody

    ICAM1 适用: 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

    anti-Intercellular Adhesion Molecule 1 (ICAM1) antibody
    anti-Intercellular Adhesion Molecule 1 (ICAM1) antibody

    ICAM1 适用: 人, 大鼠, Cow WB, FACS, ELISA, ICC, IHC (p) 宿主: 小鼠 Monoclonal MEM-111 unconjugated

    anti-Intercellular Adhesion Molecule 1 (ICAM1) (AA 102-306) antibody
    anti-Intercellular Adhesion Molecule 1 (ICAM1) (AA 102-306) antibody

    ICAM1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

    anti-Intercellular Adhesion Molecule 1 (ICAM1) (AA 41-464) antibody
    anti-Intercellular Adhesion Molecule 1 (ICAM1) (AA 41-464) antibody

    ICAM1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal 18# unconjugated

    anti-Intercellular Adhesion Molecule 1 (ICAM1) (pTyr512) antibody
    anti-Intercellular Adhesion Molecule 1 (ICAM1) (pTyr512) antibody

    ICAM1 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

    anti-Intercellular Adhesion Molecule 1 (ICAM1) (AA 41-464) antibody
    anti-Intercellular Adhesion Molecule 1 (ICAM1) (AA 41-464) antibody

    ICAM1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

    anti-Intercellular Adhesion Molecule 1 (ICAM1) (AA 27-209) antibody
    anti-Intercellular Adhesion Molecule 1 (ICAM1) (AA 27-209) antibody

    ICAM1 适用: Pig WB, IHC 宿主: 兔 Polyclonal unconjugated

    anti-Intercellular Adhesion Molecule 1 (ICAM1) (AA 313-327) antibody
    anti-Intercellular Adhesion Molecule 1 (ICAM1) (AA 313-327) antibody

    Verified ICAM1 适用: 人 WB, FACS, ELISA, IF 宿主: 山羊 Polyclonal unconjugated

    anti-Intercellular Adhesion Molecule 1 (ICAM1) (AA 1-532) antibody
    anti-Intercellular Adhesion Molecule 1 (ICAM1) (AA 1-532) antibody

    ICAM1 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 3H8-2G6 unconjugated

  • 应用备注

    Western blot, 0.1-0.5 μg/mL
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
    Immunocytochemistry/Immunofluorescence, 2 μg/mL
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells
    ELISA, 0.1-0.5 μg/mL
    1. Ballantyne, C. M., Kozak, C. A., O'Brien, W. E., Beaudet, A. L. : Assignment of the gene for intercellular adhesion molecule-1 (Icam-1) to proximal mouse chromosome 9. Genomics 9: 547-550, 1991. 2. Greve, J. M., Davis, G., Meyer, A. M., Forte, C. P., Yost, S. C., Marlor, C. W., Kamarck, M. E., McClelland, A. : The major human rhinovirus receptor is ICAM-1. Cell 56: 839-847, 1989. 3. Prieto, J., Takei, F., Gendelman, R., Christenson, B., Biberfeld, P., Patarroyo, M. : MALA-2, mouse homologue of human adhesion molecule ICAM-1 (CD54). Europ. J. Immun. 19: 1551-1557, 1989.

    限制

    仅限研究用

  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Ma, Pan, Ren, Guo, Guo, Wei, Zheng, Chen: "15-oxoeicosatetraenoic acid mediates monocyte adhesion to endothelial cell." in: Lipids in health and disease, Vol. 16, Issue 1, pp. 137, (2018) (PubMed).

    Ma, Pan, Chen, Guo, Zhao, Zheng, Chen: "Trimethylamine N-oxide in atherogenesis: impairing endothelial self-repair capacity and enhancing monocyte adhesion." in: Bioscience reports, Vol. 37, Issue 2, (2017) (PubMed).

    Wang, Sun, Shen, Wu, Liu, Yang, Ji, Ji, Li: "Octreotide Protects the Mouse Retina against Ischemic Reperfusion Injury through Regulation of Antioxidation and Activation of NF-κB." in: Oxidative medicine and cellular longevity, Vol. 2015, pp. 970156, (2016) (PubMed).

    Pan, Wang, Pu, Yao, Wang: "Effect of Puerarin on Expression of ICAM-1 and TNF-α in Kidneys of Diabetic Rats." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 21, pp. 2134-40, (2016) (PubMed).

    Wang, Wang, Li, Wu, Liu, Yang, Ji, Ji, Li: "The Neuropilin-1 Inhibitor, ATWLPPR Peptide, Prevents Experimental Diabetes-Induced Retinal Injury by Preserving Vascular Integrity and Decreasing Oxidative Stress." in: PLoS ONE, Vol. 10, Issue 11, pp. e0142571, (2016) (PubMed).

    Cheng, Zhang, Song, Feng: "Intercellular adhesion molecule-1 expression in the hippocampal CA1 region of hyperlipidemic rats with chronic cerebral ischemia." in: Neural regeneration research, Vol. 7, Issue 17, pp. 1312-7, (2015) (PubMed).

    Chen, Zhang, Chen, Liu, Wang, Zhou, Qiu, Zhang, Teng, Mao, Liu, Wei, Li: "Retinoic Acid promotes interleukin-4 plasmid-dimethylsulfoxide topical transdermal delivery for treatment of psoriasis." in: Annals of dermatology, Vol. 27, Issue 2, pp. 121-7, (2015) (PubMed).

    Ning, Liu, Lv, Yang, Zhang, Yu, Wang, Zhu: "Lipid metabolism and inflammation modulated by Vitamin D in liver of diabetic rats." in: Lipids in health and disease, Vol. 14, pp. 31, (2015) (PubMed).

    Fan, Yao, Li, Hu, Shao, Tian: "Anti-inflammatory and antioxidant effects of curcumin on acute lung injury in a rodent model of intestinal ischemia reperfusion by inhibiting the pathway of NF-Kb." in: International journal of clinical and experimental pathology, Vol. 8, Issue 4, pp. 3451-9, (2015) (PubMed).

    Wang, Zhao, Fang, Li, Shen, Cao, Zhu: "Glycyrrhizin protects against porcine endotoxemia through modulation of systemic inflammatory response." in: Critical care, Vol. 17, Issue 2, pp. R44, (2014) (PubMed).

    Fan, Jing, Yao, Li, Hu, Shao, Shen, Pan, Luo, Tian: "The protective effects of curcumin on experimental acute liver lesion induced by intestinal ischemia-reperfusion through inhibiting the pathway of NF-?B in a rat model." in: Oxidative medicine and cellular longevity, Vol. 2014, pp. 191624, (2014) (PubMed).

    Yu, Chen, Wang, Kuang, Liu, Zhang, Du: "Neuroprotective effect of kaempferol glycosides against brain injury and neuroinflammation by inhibiting the activation of NF-?B and STAT3 in transient focal stroke." in: PLoS ONE, Vol. 8, Issue 2, pp. e55839, (2013) (PubMed).

    Yu, Chen, Jiang: "Administration of pigment epithelium-derived factor delivered by adeno-associated virus inhibits blood-retinal barrier breakdown in diabetic rats." in: Molecular vision, Vol. 16, pp. 2384-94, (2011) (PubMed).

    Yao, Zhang, Zheng, Li, Wang, Wang, Chu, Hu, Liu, Tian: "Prophylaxis with carnosol attenuates liver injury induced by intestinal ischemia/reperfusion." in: World journal of gastroenterology, Vol. 15, Issue 26, pp. 3240-5, (2009) (PubMed).

    Wang, Qiao, Li, Yang: "Ginsenoside Rb1 attenuates intestinal ischemia-reperfusion- induced liver injury by inhibiting NF-kappaB activation." in: Experimental & molecular medicine, Vol. 40, Issue 6, pp. 686-98, (2008) (PubMed).

    Tian, Yao, Li, Zhang, Feng, Yang, Zheng: "Effect of nuclear factor kappa B on intercellular adhesion molecule-1 expression and neutrophil infiltration in lung injury induced by intestinal ischemia/reperfusion in rats." in: World journal of gastroenterology, Vol. 12, Issue 3, pp. 388-92, (2006) (PubMed).

    Hang, Shi, Li, Li, Yin: "Up-regulation of intestinal nuclear factor kappa B and intercellular adhesion molecule-1 following traumatic brain injury in rats." in: World journal of gastroenterology, Vol. 11, Issue 8, pp. 1149-54, (2005) (PubMed).

    Zhao, Chen, Zhou, Zhou, Li: "Influence of platelet activating factor on expression of adhesion molecules in experimental pancreatitis." in: World journal of gastroenterology, Vol. 9, Issue 2, pp. 338-41, (2003) (PubMed).

  • 抗原

    ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))

    别名

    ICAM1

    背景

    Synonyms: Intercellular adhesion molecule 1, ICAM-1, Major group rhinovirus receptor, CD54, ICAM1

    Tissue Specificity: Present in T-cells, monocytes, epithelial cells and hepatocytes (at protein level). Ubiquitously expressed, with highest levels in heart, skeletal muscle, liver, placenta and peripheral blood leukocytes. .

    Background: CD54, also known as ICAM-1. Intercellular adhesion molecule-1 (ICAM1) is a ligand for lymphocyte function-associated (LFA) antigens. ICAM-1 is an integral membrane protein, a member of the immunoglobulin superfamily, and a ligand for LFA-1, a beta 2 leukocyte integrin. This protein is the major human rhinovirus receptor. The ICAM1 gene is mapped to human chromosome 19. In humans, lymphocyte adhesion to cells is mediated by the protein heterodimer CD11a/CD18 (Leu-CAMa, LFA-1) and its ligand CD54 (ICAM-1).

    分子量

    90 kDa

    基因ID

    3383

    UniProt

    P05362

    途径

    Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling
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