SPHK2 抗体 (AA 215-269)
Quick Overview for SPHK2 抗体 (AA 215-269) (ABIN5692941)
抗原
See all SPHK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 215-269
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原理
- Anti-SPHK2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-SPHK2 Antibody Picoband® (ABIN5692941). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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免疫原
- E. coli-derived human SPHK2 recombinant protein (Position: F215-M269).
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亚型
- IgG
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anti-Sphingosine Kinase 2 (SPHK2) (AA 590-620), (C-Term) antibody
SPHK2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB03625 unconjugated
anti-Sphingosine Kinase 2 (SPHK2) (AA 1-654) antibodySPHK2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine Kinase 2 (SPHK2) (AA 101-200) antibodySPHK2 适用: 人, 小鼠, 大鼠 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine Kinase 2 (SPHK2) (N-Term) antibodySPHK2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine Kinase 2 (SPHK2) antibodySPHK2 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine Kinase 2 (SPHK2) (AA 1-654) antibodySPHK2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Sphingosine Kinase 2 (SPHK2) (Tyr754) antibodySPHK2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine Kinase 2 (SPHK2) (AA 1-30), (N-Term) antibodySPHK2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB03623 unconjugated
anti-Sphingosine Kinase 2 (SPHK2) (AA 1-30) antibodySPHK2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine Kinase 2 (SPHK2) (AA 590-620) antibodySPHK2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
Flow Cytometry (Fixed), 1-3 μg/1x106 cells
ELISA, 0.1-0.5 μg/mL
1. Hait NC, Sarkar S, Le Stunff H, Mikami A, Maceyka M, Milstien S, Spiegel S (August 2005). "Role of sphingosine kinase 2 in cell migration toward epidermal growth factor". The Journal of Biological Chemistry. 280 (33): 29462-9. 2. Liu H, Sugiura M, Nava VE, Edsall LC, Kono K, Poulton S, Milstien S, Kohama T, Spiegel S (June 2000). "Molecular cloning and functional characterization of a novel mammalian sphingosine kinase type 2 isoform". The Journal of Biological Chemistry. 275 (26): 19513-20. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- SPHK2 (Sphingosine Kinase 2 (SPHK2))
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别名
- SPHK2
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背景
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Synonyms: Sphingosine kinase 2, SK 2, SPK 2
Background: Sphingosine kinase 2 is a protein that in humans is encoded by the SPHK2 gene. This gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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分子量
- 69 kDa
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基因ID
- 56848
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途径
- VEGF Signaling
抗原
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