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PLAU 抗体 (AA 179-431)

This anti-PLAU antibody is a 兔 多克隆 antibody detecting PLAU in WB 和 ELISA. Suitable for 人, 小鼠 和 大鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN5692920
发货至: 中国

Quick Overview for PLAU 抗体 (AA 179-431) (ABIN5692920)

抗原

See all PLAU 抗体
PLAU (Plasminogen Activator, Urokinase (PLAU))

适用

  • 86
  • 28
  • 21
  • 7
  • 5
  • 5
  • 3
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 86
  • 20
  • 12
  • 5
  • 1
  • 1

克隆类型

  • 90
  • 31
  • 2
多克隆

标记

  • 77
  • 15
  • 10
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
This PLAU antibody is un-conjugated

应用范围

  • 87
  • 56
  • 52
  • 27
  • 26
  • 16
  • 12
  • 11
  • 10
  • 9
  • 6
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 7
    • 6
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 179-431

    原理

    Anti-PLAU Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-PLAU Antibody Picoband® (ABIN5692920). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    免疫原

    E. coli-derived human PLAU recombinant protein (Position: I179-L431).

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL
    ELISA, 0.1-0.5 μg/mL
    1. Degryse, Bernard (1 June 2011). "The urokinase receptor system as strategic therapeutic target: challenges for the 21st century". Current Pharmaceutical Design. 17 (19): 1872-1873. 2. Tang, Linlin, Han, Xiuzhen (March 2013). "The urokinase plasminogen activator system in breast cancer invasion and metastasis". Biomedicine & Pharmacotherapy. 67 (2): 179-182.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Wu, Li, Liu, Ning, Li: "Effects of Guiyuanfang and autologous transplantation of bone marrow stem cells on rats with liver fibrosis." in: World journal of gastroenterology, Vol. 11, Issue 8, pp. 1155-60, (2005) (PubMed).

  • 抗原

    PLAU (Plasminogen Activator, Urokinase (PLAU))

    别名

    PLAU

    背景

    Synonyms: Urokinase-type plasminogen activator, U-plasminogen activator, uPA, Urokinase-type plasminogen activator long chain A, Urokinase-type plasminogen activator short chain A, Urokinase-type plasminogen activator chain B, PLAU

    Tissue Specificity: Expressed in the prostate gland and prostate cancers.

    Background: Urokinase, also known as urokinase-type plasminogen activator (uPA), is a serine protease present in humans and other animals. This gene encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen activator (HMW-uPA). HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA). This low molecular weight form does not bind to the urokinase-type plasminogen activator receptor. Mutations in this gene may be associated with Quebec platelet disorder and late-onset Alzheimer's disease. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

    分子量

    48 kDa

    基因ID

    5328

    UniProt

    P00749

    途径

    Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration
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