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IL17C 抗体 (AA 19-197)

This anti-IL17C antibody is a 兔 多克隆 antibody detecting IL17C in WB 和 ELISA. Suitable for 人 和 小鼠.
产品编号 ABIN5692880
发货至: 中国

Quick Overview for IL17C 抗体 (AA 19-197) (ABIN5692880)

抗原

See all IL17C 抗体
IL17C (Interleukin 17C (IL17C))

适用

  • 42
  • 24
  • 19
  • 3
人, 小鼠

宿主

  • 40
  • 8
  • 2
  • 1
  • 1

克隆类型

  • 43
  • 9
多克隆

标记

  • 28
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This IL17C antibody is un-conjugated

应用范围

  • 39
  • 17
  • 16
  • 14
  • 13
  • 13
  • 9
  • 5
  • 5
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 15
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 19-197

    原理

    Anti-IL17C Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-IL17C Antibody Picoband® (ABIN5692880). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    免疫原

    E. coli-derived human IL17C recombinant protein (Position: H19-V197).

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL
    ELISA (Cap), 1-5 μg/mL
    1. Chang, S. H., Reynolds, J. M., Pappu, B. P., Chen, G., Martinez, G. J., Dong, C. Interleukin-17C promotes Th17 cell responses and autoimmune disease via interleukin-17 receptor E.Immunity 35: 611-621, 2011. 2. Conti, H. R., Whibley, N., Coleman, B. M., Garg, A. V., Jaycox, J. R., Gaffen, S. L. Signaling through IL-17C/IL-17RE is dispensable for immunity to systemic, oral and cutaneous candidiasis. PLoS One 10: e0122807, 2015.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    IL17C (Interleukin 17C (IL17C))

    别名

    IL17C

    背景

    Synonyms: Interleukin-17C, IL-17C, Cytokine CX2, IL17C, UNQ561/PRO1122

    Tissue Specificity: Found in serum and urine.

    Background: IL17C, also known as CX2, is a protein that in humans is encoded by the IL17C gene. IL17C is mapped to 16q24.3. The protein encoded by this gene is a T cell-derived cytokine that shares the sequence similarity with IL17. This cytokine was reported to stimulate the release of tumor necrosis factor alpha and interleukin 1 beta from a monocytic cell line. The expression of this cytokine was found to be restricted to activated T cells. IL17C is an essential autocrine cytokine regulating innate epithelial immune responses. It also plays an important role in the pathogenesis of inflammatory arthritis.

    分子量

    29 kDa

    基因ID

    27189

    UniProt

    Q9P0M4

    途径

    Cellular Response to Molecule of Bacterial Origin
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