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Topoisomerase I 抗体 (AA 526-765)

The 兔 多克隆 anti-Topoisomerase I antibody (ABIN5692844) specifically detects Topoisomerase I in WB, ELISA, IF 和 ICC. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN5692844
发货至: 中国
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Quick Overview for Topoisomerase I 抗体 (AA 526-765) (ABIN5692844)

抗原

See all Topoisomerase I (TOP1) 抗体
Topoisomerase I (TOP1) (Topoisomerase (DNA) I (TOP1))

适用

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人, 小鼠, 大鼠

宿主

  • 61
  • 11
  • 2

克隆类型

  • 42
  • 32
多克隆

标记

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This Topoisomerase I antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

    • 11
    • 8
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    AA 526-765

    原理

    Anti-Topoisomerase I/TOP1 Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-Topoisomerase I/TOP1 Antibody (ABIN5692844). Tested in ELISA, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived human Topoisomerase I recombinant protein (Position: E526-F765).

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL
    Immunocytochemistry/Immunofluorescence, 2 μg/mL
    ELISA, 0.1-0.5 μg/mL

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    Topoisomerase I (TOP1) (Topoisomerase (DNA) I (TOP1))

    别名

    TOP1

    背景

    Synonyms: DNA topoisomerase 1, DNA topoisomerase I, TOP1,

    Tissue Specificity: Endothelial cells.

    Background: DNA topoisomerase 1 is an enzyme that in humans is encoded by the TOP1 gene. This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22.

    分子量

    100 kDa

    基因ID

    7150

    UniProt

    P11387

    途径

    Caspase Cascade in Apoptosis, Stem Cell Maintenance
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