POLL 抗体 (AA 307-407)
Quick Overview for POLL 抗体 (AA 307-407) (ABIN5692843)
抗原
See all POLL 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 307-407
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原理
- Anti-DNA Polymerase lambda/POLL Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-DNA Polymerase lambda/POLL Antibody Picoband® (ABIN5692843). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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免疫原
- E. coli-derived human DNA Polymerase lambda recombinant protein (Position: K307-N407).
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亚型
- IgG
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应用备注
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Western blot, 0.1-0.5 μg/mL
Flow Cytometry (Fixed), 1-3 μg/1x106 cells
ELISA, 0.1-0.5 μg/mL
1. "Entrez Gene: POLL polymerase (DNA ed), lambda". 2. García-Díaz M, Bebenek K, Kunkel TA, Blanco L (September 2001). "Identification of an intrinsic 5'-deoxyribose-5-phosphate lyase activity in human DNA polymerase lambda: a possible role in base excision repair". J. Biol. Chem. 276 (37): 34659-63. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- POLL (Polymerase (DNA Directed), lambda (POLL))
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别名
- POLL
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背景
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Synonyms: DNA polymerase lambda , Pol Lambda
Tissue Specificity: Expressed in a number of tissues. Abundant in testis.
Background: DNA polymerase lambda, also known as POLL, is a protein found in eukaryotes. In humans, it is encoded by the POLLA gene. POLL has 5-prime-deoxyribose-5-phosphate lyase activity and strand-displacement synthesis activity on gapped DNA substrates, suggesting that POLL participates in short- and long-patch base excision repair. POLL is widely expressed, with abundant expression in pachytene spermatocytes of testis and in ovary.
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分子量
- 70 kDa
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基因ID
- 27343
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途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
抗原
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