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Betacellulin 抗体 (AA 32-177)

This anti-Betacellulin antibody is a 兔 多克隆 antibody detecting Betacellulin in WB, IHC 和 ELISA. Suitable for 小鼠 和 大鼠.
产品编号 ABIN5692803
发货至: 中国

Quick Overview for Betacellulin 抗体 (AA 32-177) (ABIN5692803)

抗原

See all Betacellulin (BTC) 抗体
Betacellulin (BTC)

适用

  • 53
  • 37
  • 12
  • 2
  • 2
  • 1
小鼠, 大鼠

宿主

  • 75
  • 7
  • 1
  • 1

克隆类型

  • 78
  • 6
多克隆

标记

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  • 12
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Betacellulin antibody is un-conjugated

应用范围

  • 76
  • 29
  • 20
  • 19
  • 16
  • 13
  • 13
  • 8
  • 7
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

    • 15
    • 9
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    AA 32-177

    原理

    Anti-Betacellulin/Btc Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-Betacellulin/Btc Antibody Picoband® (ABIN5692803). Tested in ELISA, IHC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    免疫原

    E. coli-derived rat Betacellulin recombinant protein (Position: D32-A177).

    亚型

    IgG
  • 应用备注

    Western blot,0.1-0.5 μg/mL
    Immunohistochemistry (Paraffin-embedded Section),0.5-1 μg/mL
    ELISA,0.1-0.5 μg/mL
    1. Elbein SC, Wang X, Karim MA, et al. (2006). "Analysis of coding variants in the betacellulin gene in type 2 diabetes and insulin secretion in African American subjects.". BMC Med. Genet. 7: 62. 2. Kim HS, Shin HS, Kwak HJ, Cho CH, Lee CO, Koh GY (February 2003). "Betacellulin induces angiogenesis through activation of mitogen-activated protein kinase and phosphatidylinositol 3'-kinase in endothelial cell". FASEB J. 17 (2): 318-20.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    Betacellulin (BTC)

    别名

    Btc

    背景

    Synonyms: Betacellulin

    Tissue Specificity: Highly expressed in testis.

    Background: Betacellulin is a protein that in humans is encoded by the BTC gene located on chromosome 4 at locus 4q13-q21. This gene encodes a member of the epidermal growth factor (EGF) family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the secreted growth factor. A secreted form and a membrane-anchored form of this protein bind to multiple different EGF receptors. This protein promotes pancreatic cell proliferation and insulin secretion, as well as retinal vascular permeability. Mutations in this gene may be associated with type 2 diabetes in human patients.

    分子量

    26 kDa

    基因ID

    64022

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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