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CD80 抗体 (AA 35-244)

Name: CD80 抗体 (AA 35-244)
SKU: ABIN5692796
Availability: OutOfStock

CD80 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

IHC analysis of CD80 using anti-CD80 antibody . (CD80 抗体 (AA 35-244))

IHC

2 images

(1 reference)

产品编号 ABIN5692796

发货至: 中国

Datasheet as PDF

抗原 See all CD80 抗体

CD80
抗原表位
15

14

8

8

6

6

4

4

4

4

3

3

3

2

2

1

1

1

1

1

1

1

1

1
AA 35-244
适用
138

92

37

6

6

5

1

1
人, 小鼠, 大鼠
宿主
93

62

18

16

11

2

1
兔
Compatible Secondaries
克隆类型
124

76

2
多克隆
标记
88

16

15

14

9

5

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
This CD80 antibody is un-conjugated
应用范围
115

88

71

34

34

21

14

12

12

11

10

10

8

5

4

2

2

2

1

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

原理

Anti-CD80 Antibody Picoband®

交叉反应（详细）

No cross-reactivity with other proteins.

产品特性

Anti-CD80 Antibody Picoband® (ABIN5692796). Tested in ELISA, IF, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

免疫原

E. coli-derived human CD80 recombinant protein (Position: V35-L244).

亚型

IgG

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CD80 适用: 人 FACS, ELISA, IHC 宿主: 小鼠 Monoclonal 1G3D7 unconjugated

anti-CD80 (CD80) (AA 251-321) antibody
CD80 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), ICC, IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated

anti-CD80 (CD80) (AA 38-246) antibody
CD80 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-CD80 (CD80) antibody
CD80 适用: 小鼠, 犬 FACS, IP, IHC (fro) 宿主: 仓鼠 Monoclonal 16-10A1 unconjugated

anti-CD80 (CD80) (Extracellular Domain) antibody (PerCP)
CD80 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-233 PerCP

anti-CD80 (CD80) antibody
CD80 适用: 人 ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 2A2 unconjugated

anti-CD80 (CD80) (AA 111-265) antibody
CD80 适用: 人, 小鼠, 大鼠 FACS, WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-CD80 (CD80) (AA 1-100) antibody
CD80 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-CD80 (CD80) (AA 35-288) antibody
CD80 适用: 人 ELISA, PLA 宿主: 小鼠 Monoclonal 1G1 unconjugated

anti-CD80 (CD80) (AA 1-288) antibody
CD80 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL
Immunofluorescence, 5 μg/mL
ELISA, 0.1-0.5 μg/mL
1. Peach, R J, Bajorath J, Naemura J, Leytze G, Greene J, Aruffo A, Linsley P S (Sep. 1995). "Both extracellular immunoglobin-like domains of CD80 contain residues critical for binding T cell surface receptors CTLA-4 and CD28". J. Biol. Chem. (UNITED STATES) 270 (36): 21181-7. 2. Stamper, C C, Zhang Y, Tobin J F, Erbe D V, Ikemizu S, Davis S J, Stahl M L, Seehra J, Somers W S, Mosyak L (Mar. 2001). "Crystal structure of the B7-1/CTLA-4 complex that inhibits human immune responses". Nature (England) 410 (6828): 608-11.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Du, Dong, Zhao, Fu, Wang, Chen, Ou, Li, Sun, Tang, Song: "Immunostimulatory and anti-neoplasm effects of a novel palindrome CpG oligodeoxynucleotide in mice." in: Acta pharmacologica Sinica, Vol. 33, Issue 8, pp. 1047-54, (2012) (PubMed).
抗原

CD80

别名

CD80 (CD80 产品)

背景

Synonyms: T-lymphocyte activation antigen CD80, Activation B7-1 antigen, BB1, CTLA-4 counter-receptor B7.1, B7, CD80, CD80, CD28LG, CD28LG1, LAB7
Tissue Specificity: Hematopoietic stem and progenitor cell- enriched populations. Found in brain, placenta and testis.
Background: Cluster of Differentiation 80 (also CD80 and B7-1) is a protein found on activated B cells and monocytes that provides a costimulatory signal necessary for T cell activation and survival. It is the ligand for two different proteins on the T cell surface: CD28 (for autoregulation and intercellular association) and CTLA-4 (for attenuation of regulation and cellular disassociation). CD80 works in tandem with CD86 to prime T cells. The CD80 genes encode B7-1 which are structurally similar members of the immunoglobulin superfamily expressed on a variety of hematopoietic cell types.

分子量

103 kDa

基因ID

941

UniProt

P33681

途径

TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints