AKR1C2 抗体 (AA 1-123)
Quick Overview for AKR1C2 抗体 (AA 1-123) (ABIN5692785)
抗原
See all AKR1C2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-123
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原理
- Anti-AKR1C1/C2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-AKR1C1/C2 Antibody Picoband® (ABIN5692785). Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived human AKR1C1/C2 recombinant protein (Position: M1-K123).
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亚型
- IgG
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anti-Aldo-keto Reductase Family 1, Member C2 (AKR1C2) (AA 1-323) antibody
AKR1C2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Aldo-keto Reductase Family 1, Member C2 (AKR1C2) antibodyAKR1C2 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal CPTC-AKR1C2-1 unconjugated
anti-Aldo-keto Reductase Family 1, Member C2 (AKR1C2) (AA 224-323) antibodyAKR1C2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Aldo-keto Reductase Family 1, Member C2 (AKR1C2) (AA 1-323) antibodyAKR1C2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Aldo-keto Reductase Family 1, Member C2 (AKR1C2) (AA 224-323) antibodyAKR1C2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3C11 unconjugated
anti-Aldo-keto Reductase Family 1, Member C2 (AKR1C2) antibodyAKR1C2 适用: 人, 大鼠, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Aldo-keto Reductase Family 1, Member C2 (AKR1C2) (AA 1-323) antibodyAKR1C2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Aldo-keto Reductase Family 1, Member C2 (AKR1C2) (N-Term) antibodyAKR1C2 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Aldo-keto Reductase Family 1, Member C2 (AKR1C2) (Internal Region) antibodyAKR1C2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Aldo-keto Reductase Family 1, Member C2 (AKR1C2) (AA 1-323) antibodyAKR1C2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Ciaccio PJ, Tew KD (Jun 1994). "cDNA and deduced amino acid sequences of a human colon dihydrodiol dehydrogenase". Biochimica et Biophysica Acta 1186 (1-2): 129-32. 2. O'connor T, Ireland LS, Harrison DJ, Hayes JD (Oct 1999). "Major differences exist in the function and tissue-specific expression of human aflatoxin B1 aldehyde reductase and the principal human aldo-keto reductase AKR1 family members". The Biochemical Journal 343 (2): 487-504. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))
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别名
- AKR1C2
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背景
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Synonyms: Aldo-keto reductase family 1 member C2,1.-.-.-,3-alpha-HSD3,Chlordecone reductase homolog HAKRD,Dihydrodiol dehydrogenase 2,DD-2,DD2,Dihydrodiol dehydrogenase/bile acid-binding protein,DD/BABP,Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase,1.3.1.20 ,Type III 3-alpha-hydroxysteroid dehydrogenase,1.1.1.357 ,AKR1C2,DDH2,
Tissue Specificity: Expressed in fetal testes. Expressed in fetal and adult adrenal glands. .
Background: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. And this gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding two different isoforms have been found for this gene.
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分子量
- 37 kDa
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基因ID
- 1645, 1646
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UniProt
- P52895
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途径
- Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process
抗原
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