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AKR1C2 抗体 (AA 1-123)

This 兔 多克隆 antibody specifically detects AKR1C2 in WB, IF, ICC 和 FACS. It exhibits reactivity toward 人, 大鼠 和 小鼠.
产品编号 ABIN5692785
发货至: 中国
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Quick Overview for AKR1C2 抗体 (AA 1-123) (ABIN5692785)

抗原

See all AKR1C2 抗体
AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))

适用

  • 53
  • 5
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
人, 大鼠, 小鼠

宿主

  • 36
  • 17

克隆类型

  • 39
  • 14
多克隆

标记

  • 29
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This AKR1C2 antibody is un-conjugated

应用范围

  • 43
  • 24
  • 21
  • 10
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)
  • 抗原表位

    • 10
    • 7
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-123

    原理

    Anti-AKR1C1/C2 Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-AKR1C1/C2 Antibody (ABIN5692785). Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived human AKR1C1/C2 recombinant protein (Position: M1-K123).

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))

    别名

    AKR1C2

    背景

    Synonyms: Aldo-keto reductase family 1 member C2,1.-.-.-,3-alpha-HSD3,Chlordecone reductase homolog HAKRD,Dihydrodiol dehydrogenase 2,DD-2,DD2,Dihydrodiol dehydrogenase/bile acid-binding protein,DD/BABP,Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase,1.3.1.20 ,Type III 3-alpha-hydroxysteroid dehydrogenase,1.1.1.357 ,AKR1C2,DDH2,

    Tissue Specificity: Expressed in fetal testes. Expressed in fetal and adult adrenal glands. .

    Background: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. And this gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding two different isoforms have been found for this gene.

    分子量

    37 kDa

    基因ID

    1645, 1646

    UniProt

    P52895

    途径

    Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process
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