GZMB 抗体 (AA 21-247)
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Quick Overview for GZMB 抗体 (AA 21-247) (ABIN5692783)
抗原
See all GZMB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 21-247
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原理
- Anti-Granzyme B/Gzmb Antibody
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-Granzyme B/Gzmb Antibody. Tested in ELISA, WB applications. This antibody reacts with Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived mouse Granzyme B recombinant protein (Position: I21-S247).
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亚型
- IgG
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应用备注
- Western blot, 0.1-0.5 μg/mL ELISA, 0.1-0.5 μg/mL
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- GZMB (Granzyme B (GZMB))
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别名
- Gzmb
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背景
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Background: Granzyme B is a serine protease that in humans is encoded by the GZMB gene. Granzyme B is expressed by cytotoxic T lymphocytes (CTL) and natural killer (NK) cells. CTL and NK cells share the remarkable ability to recognize specific infected target cells. They are thought to protect their host by inducing apoptosis of cells that bear on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein encoded by this gene is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response.
Gene Full Name: granzyme B
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分子量
- 28 kDa
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基因ID
- 14939
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UniProt
- P04187
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途径
- Apoptosis, Caspase Cascade in Apoptosis
抗原
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