电话:: +86 (0512) 65829739
传真:: +86 (010) 6788 5057
电子邮件:: orders@antibodies-online.cn

我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

GZMB 抗体 (AA 21-247)

This anti-GZMB antibody is a 兔多克隆 antibody detecting GZMB in WB 和 ELISA. Suitable for 小鼠和大鼠.

Western blot analysis of Granzyme B using anti-Granzyme B antibody . (GZMB 抗体 (AA 21-247))

1 image

产品编号 ABIN5692783

发货至: 中国

Datasheet as PDF

Quick Overview for GZMB 抗体 (AA 21-247) (ABIN5692783)

抗原

See all GZMB 抗体

GZMB (Granzyme B (GZMB))

适用

179
50
25
12
4
4
3
1
1

小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This GZMB antibody is un-conjugated

应用范围

91
83
43
42
30
24
20
18
14
13
13
10
6
6
5
2
2
2
1
1
1
1
1
1

Western Blotting (WB), ELISA

Discover our top product GZMB Primary Antibody

抗原表位
53

20

16

10

10

4

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
AA 21-247

原理

Anti-Granzyme B/Gzmb Antibody Picoband®

交叉反应（详细）

No cross-reactivity with other proteins.

产品特性

Anti-Granzyme B/Gzmb Antibody Picoband® (ABIN5692783). Tested in ELISA, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

免疫原

E. coli-derived mouse Granzyme B recombinant protein (Position: I21-S247).

亚型

IgG
anti-Granzyme B (GZMB) (AA 21-247) antibody
GZMB 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Granzyme B (GZMB) (AA 73-187) antibody
GZMB 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal GZMB-3014 unconjugated

anti-Granzyme B (GZMB) (AA 21-130) antibody
GZMB 适用: 人, 小鼠 WB, ELISA, FACS, IHC (p), IF (p), IHC (fro), IF (cc) 宿主: 兔 Polyclonal unconjugated

anti-Granzyme B (GZMB) (AA 1-247) antibody
GZMB 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-Granzyme B (GZMB) (AA 73-187) antibody
GZMB 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal GZMB-3056 unconjugated

anti-Granzyme B (GZMB) antibody
GZMB 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Granzyme B (GZMB) antibody
GZMB 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal CLB-GB11 unconjugated

anti-Granzyme B (GZMB) (AA 21-247) antibody
GZMB 适用: 人 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 4E4 unconjugated

anti-Granzyme B (GZMB) (AA 21-247) antibody
GZMB 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 2G12G7 unconjugated

anti-Granzyme B (GZMB) antibody
GZMB 适用: 人 ELISA, FACS, cELISA 宿主: 小鼠 Monoclonal GM-4C1 unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL
ELISA, 0.1-0.5 μg/mL
1. Huang, C., Bi, E., Hu. Y., Deng, W., Tian, Z., Dong, C., Hu, Y., Sun, B.A novel NF-kappa-B binding site controls human granzyme B gene transcription.J. Immun. 176: 4173-4181, 2006. 2. Motyka, B., Korbutt, G., Pinkoski, M. J., Heibein, J. A., Caputo, A., Hobman, M., Barry, M., Shostak, I., Sawchuk, T., Holmes, C. F. B., Gauldie, J., Bleackley, R. C.Mannose 6-phosphate/insulin-like growth factor II receptor is a death receptor for granzyme B during cytotoxic T cell-induced apoptosis.Cell 103: 491-500, 2000. 3. Winrow, C. J., Pankratz, D. G., Vibat, C. R. T., Bowen, T. J., Callahan, M. A., Warren, A. J., Hilbush, B. S., Wynshaw-Boris, A., Hasel, K. W., Weaver, Z., Lockhart, D. J., Barlow, C.Aberrant recombination involving the granzyme locus occurs in Atm-/- T-cell lymphomas.Hum. Molec. Genet. 14: 2671-2684, 2005.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
抗原

GZMB (Granzyme B (GZMB))

别名

Gzmb

背景

Synonyms: Granzyme B (G,H), CTLA-1, Cytotoxic cell protease 1, CCP1, Fragmentin-2, Gzmb, Ctla-1, Ctla1
Tissue Specificity: Isoform A is expressed in fetal liver and in hematopoietic tissues and choroid plexus. In adults highest expression in heart, liver, small intestine, prostate and ovary. Low level in lung and kidney. Isoform B is highly expressed in hypothalamus.
Background: Granzyme B is a serine protease that in humans is encoded by the GZMB gene. Granzyme B is expressed by cytotoxic T lymphocytes (CTL) and natural killer (NK) cells. CTL and NK cells share the remarkable ability to recognize specific infected target cells. They are thought to protect their host by inducing apoptosis of cells that bear on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein encoded by this gene is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response.

分子量

28 kDa

基因ID

14939

UniProt

P04187

途径

Apoptosis, Caspase Cascade in Apoptosis

You are here: