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BTLA 抗体

This anti-BTLA antibody is a 大鼠 单克隆 antibody detecting BTLA in FACS, ELISA 和 Func. Suitable for 人.
产品编号 ABIN5690631
发货至: 中国

Quick Overview for BTLA 抗体 (ABIN5690631)

抗原

See all BTLA 抗体
BTLA (B and T Lymphocyte Associated (BTLA))

适用

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宿主

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大鼠

克隆类型

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单克隆

标记

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This BTLA antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), ELISA, Functional Studies (Func)

克隆位点

6F4
  • 特异性

    Recognizes human BTLA.

    纯度

    > 95% (SDS-PAGE)

    免疫原

    Ectodomain of human BTLA fused to human IgG Fc.

    亚型

    IgG1
  • 应用备注

    Immunohistochemistry: (frozen sections).

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid. In PBS containing 10 % glycerol.

    储存条件

    -20 °C

    储存方法

    Stable for at least 1 year after receipt when stored at -20°C.
  • 抗原

    BTLA (B and T Lymphocyte Associated (BTLA))

    别名

    BTLA

    背景

    B and T lymphocyte associated (BTLA) is an Ig domain superfamily protein with cytoplasmic immunoreceptor tyrosine-based inhibitory motifs. The herpes virus entry mediator (HVEM), a member of the TNF receptor (TNFR) superfamily, can act as a molecular switch that modulates T cell activation by propagating positive signals from the TNF-related ligand LIGHT (TNFR superfamily 14), or inhibitory signals through the Ig superfamily member BTLA. The binding site on HVEM for BTLA is conserved in the orphan TNF receptor UL144, present in human CMV. UL144 binds BTLA, but not LIGHT, and inhibits T cell proliferation, selectively mimicking the inhibitory cosignaling function of HVEM.

    基因ID

    151888

    NCBI登录号

    NP_861445

    UniProt

    Q7Z6A9

    途径

    Cancer Immune Checkpoints
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