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Osteopontin 抗体 (AA 50-100)

This anti-Osteopontin antibody is a 兔 多克隆 antibody detecting Osteopontin in WB, ELISA, IHC (p) 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN5690268
发货至: 中国

Quick Overview for Osteopontin 抗体 (AA 50-100) (ABIN5690268)

抗原

See all Osteopontin (SPP1) 抗体
Osteopontin (SPP1) (Secreted phosphoprotein 1 (SPP1))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This Osteopontin antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
  • 抗原表位

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    AA 50-100

    特异性

    SPP1 antibody is human, mouse and rat reactive. Multiple isoforms of SPP1 are known to exist.

    纯化方法

    SPP1 Antibody is affinity chromatography purified via peptide column.

    免疫原

    SPP1 antibody was raised against an 18 amino acid peptide near the amino terminus of human SPP1.

    The immunogen is located within amino acids 50 - 100 of SPP1.

    亚型

    IgG
  • 应用备注

    SPP1 antibody can be used for detection of SPP1 by Western blot at 1 - 2 μ,g/mL.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    SPP1 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    SPP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原

    Osteopontin (SPP1) (Secreted phosphoprotein 1 (SPP1))

    别名

    SPP1

    背景

    SPP1 Antibody: The secreted protein 1 (SPP1), also known as osteopontin, is a major noncollagenous protein of bone, but is also found in the extracellular matrix of other mineralized tissues and in bodily fluids. In bone, SPP1 is produced by osteoblasts, osteocytes, macrophages, and osteoclasts (1,2). SPP1 binds to cells through integrin and non-integrin receptors, as well as the adhesion receptor CD44 in an RGD-independent manner, enabling SPP1 to induce a number of functional effects including macrophage chemotaxis, cytoprotection, and regulation of T helper type 1 cells (2). SPP1 can regulate biomineralization by inhibiting the formation of hydroxyapatite (3) and the growth of calcium oxalate crystals (4).

    分子量

    Predicted: 36 kDa

    Observed: 37 kDa

    基因ID

    6696

    NCBI登录号

    NP_001238759

    UniProt

    P10451

    途径

    Regulation of Cell Size
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