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RNF20 抗体 (AA 130-180)

This anti-RNF20 antibody is a 兔 多克隆 antibody detecting RNF20 in WB, ELISA, IF 和 IHC (p). Suitable for 人 和 小鼠.
产品编号 ABIN5690232
发货至: 中国

Quick Overview for RNF20 抗体 (AA 130-180) (ABIN5690232)

抗原

See all RNF20 抗体
RNF20 (Ring Finger Protein 20 (RNF20))

适用

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人, 小鼠

宿主

  • 59
  • 7

克隆类型

  • 52
  • 14
多克隆

标记

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This RNF20 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 7
    • 4
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    AA 130-180

    特异性

    Multiple isoforms of RNF20 are known to exist.

    纯化方法

    RNF20 Antibody is affinity chromatography purified via peptide column.

    免疫原

    RNF20 antibody was raised against a 19 amino acid peptide near the amino terminus of human RNF20.

    The immunogen is located within amino acids 130 - 180 of RNF20.

    亚型

    IgG
  • 应用备注

    RNF20 antibody can be used for detection of RNF20 by Western blot at 1 - 2 μ,g/mL.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    RNF20 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    RNF20 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原

    RNF20 (Ring Finger Protein 20 (RNF20))

    别名

    RNF20

    背景

    RNF20 Antibody: RNF20 is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B. RNF20 selectively suppresses the expression of some genes such as several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor by interfering with chromatin recruitment of transcription elongation factor SII (TFIIS). In contrast, RNF20 also positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes. Together with the deubiquitinase USP44, RNF20 regulates stem cell differentiation by modulating H2B monoubiquitination.

    分子量

    Predicted: 99, 107 kDa

    Observed: 100, 110 kDa

    基因ID

    56254

    NCBI登录号

    NP_062538

    UniProt

    Q5VTR2
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