PINK1 抗体 (AA 120-170)
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- 抗原 See all PINK1 抗体
- PINK1 (PTEN Induced Putative Kinase 1 (PINK1))
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抗原表位
- AA 120-170
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PINK1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- PINK1 antibody is human, mouse and rat reactive. At least two isoforms are known to exist, this antibody will only detect the longer isoform. PINK1 antibody will detect the cleaved and uncleaved form of PINK1.
- 纯化方法
- PINK1 antibody is affinity chromatography purified via peptide column.
- 免疫原
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PINK1 antibody was raised against a 16 amino acid peptide near the amino terminus of human PINK1.
The immunogen is located within amino acids 120 - 170 of PINK1. - 亚型
- IgG
- Top Product
- Discover our top product PINK1 Primary Antibody
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anti-PTEN Induced Putative Kinase 1 (PINK1) (AA 282-581) antibody
PINK1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-PTEN Induced Putative Kinase 1 (PINK1) (Internal Region) antibodyVerified PINK1 适用: 人 WB, ELISA, FACS 宿主: 山羊 Polyclonal unconjugated
anti-PTEN Induced Putative Kinase 1 (PINK1) (AA 112-273) antibodyPINK1 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 3A9F8 unconjugated
anti-PTEN Induced Putative Kinase 1 (PINK1) antibodyPINK1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 小鼠 Monoclonal 38CT20-8-5 unconjugated
anti-PTEN Induced Putative Kinase 1 (PINK1) (AA 112-273) antibodyPINK1 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 5F2B11 unconjugated
anti-PTEN Induced Putative Kinase 1 (PINK1) (AA 112-496) antibodyPINK1 适用: 人 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S4-15 unconjugated
anti-PTEN Induced Putative Kinase 1 (PINK1) (AA 112-496) antibody (HRP)PINK1 适用: 人 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S4-15 HRP
anti-PTEN Induced Putative Kinase 1 (PINK1) (AA 112-496) antibody (FITC)PINK1 适用: 人 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S4-15 FITC
anti-PTEN Induced Putative Kinase 1 (PINK1) (AA 112-496) antibody (Biotin)PINK1 适用: 人 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S4-15 Biotin
anti-PTEN Induced Putative Kinase 1 (PINK1) (AA 112-496) antibody (PE)PINK1 适用: 人 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S4-15 PE
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- 应用备注
- PINK1 antibody can be used for detection of PINK1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PINK1 antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- PINK1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- 抗原
- PINK1 (PTEN Induced Putative Kinase 1 (PINK1))
- 别名
- PINK1 (PINK1 产品)
- 别名
- BEST:GH23468 antibody, CG4523 antibody, Dmel\\CG4523 antibody, PINK antibody, PINK1 antibody, dPINK1 antibody, dPink1 antibody, pink1 antibody, wu:fc39e12 antibody, zgc:101729 antibody, BRPK antibody, PARK6 antibody, 1190006F07Rik antibody, AU042772 antibody, AW557854 antibody, mFLJ00387 antibody, PTEN-induced putative kinase 1 antibody, PTEN induced putative kinase 1 antibody, Pink1 antibody, PINK1 antibody, pink1 antibody
- 背景
- The PTEN-induced putative kinase 1 (PINK1) is a serine/threonine protein kinase that localizes to mitochondria and is thought to protect cells from stress-induced mitochondrial dysfunction (reviewed in 1). PINK1 recruits the E3 ubiquitin ligase Parkin to mitochondria to initiate mitophagy, an autophagic process that clears damaged mitochondria within a cell (2). PINK1 is cleaved by the mitochondrial protease PARL (3). Mutations in this gene cause one form of autosomal recessive early-onset Parkinson disease (4).
- 分子量
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Predicted: 55 kDa
Observed: 53 kDa - 基因ID
- 65018
- NCBI登录号
- NP_115785
- UniProt
- Q9BXM7
- 途径
- Autophagy
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