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OLIG2 抗体 (AA 80-130)

This anti-OLIG2 antibody is a 兔 多克隆 antibody detecting OLIG2 in WB, ELISA, IF 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN5690088
发货至: 中国

Quick Overview for OLIG2 抗体 (AA 80-130) (ABIN5690088)

抗原

See all OLIG2 抗体
OLIG2 (Oligodendrocyte Lineage Transcription Factor 2 (OLIG2))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This OLIG2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 80-130

    特异性

    OLIG2 antibody is human, mouse and rat reactive. It is predicted to not cross-react with other members of the OLIG family of proteins. At least three isoforms of OLIG2 are known to exist, this antibody will detect all three isoforms.

    纯化方法

    OLIG2 antibody is affinity chromatography purified via peptide column.

    免疫原

    OLIG2 antibody was raised against a 15 amino acid peptide near the amino terminus of human OLIG2.

    The immunogen is located within amino acids 80 - 130 of OLIG2.

    亚型

    IgG
  • 应用备注

    OLIG2 antibody can be used for detection of OLIG2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry at 5 μ,g/mL. For Immunoflorescence start at 20 μ,g/mL.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    OLIG2 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    OLIG2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原

    OLIG2 (Oligodendrocyte Lineage Transcription Factor 2 (OLIG2))

    别名

    OLIG2

    背景

    The oligodendrocyte transcription factors 1 and 2 (OLIG1 and OLIG2, respectively) make up part of basic helix-loop-helix (bHLH) family of transcription factors that are specifically expressed in zones of the neuroepithelium from which oligodendrocyte precursors emerge (1). Both OLIG1 and OLIG2 genes are downstream targets of Sonic hedgehog and are expressed exclusively in the central nervous system (2). OLIG2 is first observed in the ventral most p3 progenitor domain of the ventral neural tube while OLIG1 is first expressed in the dorsal portion of the p3 domain (2). Mice overexpressing OLIG2 exhibit impaired potassium channel expression in neural progenitors and proliferation of these cells similar to that seen in Down Syndrome, suggesting that OLIG2 may play a role in this pathology (3).

    分子量

    Predicted: 36 kDa

    Observed: 37 kDa

    基因ID

    10215

    NCBI登录号

    NP_005797

    UniProt

    Q13516
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