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NOX3 抗体 (AA 110-160)

This anti-NOX3 antibody is a 兔 多克隆 antibody detecting NOX3 in ELISA, WB, IHC (p) 和 IF. Suitable for 人 和 小鼠.
产品编号 ABIN5690083
发货至: 中国

Quick Overview for NOX3 抗体 (AA 110-160) (ABIN5690083)

抗原

See all NOX3 抗体
NOX3 (NADPH Oxidase 3 (NOX3))

适用

  • 39
  • 16
  • 7
人, 小鼠

宿主

  • 42

克隆类型

  • 42
多克隆

标记

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  • 1
  • 1
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  • 1
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This NOX3 antibody is un-conjugated

应用范围

  • 32
  • 19
  • 13
  • 13
  • 10
  • 6
  • 3
  • 2
  • 2
  • 1
ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
  • 抗原表位

    • 15
    • 8
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 110-160

    特异性

    NOX3 antibody is human and mouse reactive. NOX3 is predicted to not cross-react with other NOX proteins.

    纯化方法

    NOX3 antibody is affinity chromatography purified via peptide column.

    免疫原

    NOX3 antibody was raised against a 15 amino acid peptide near the amino terminus of human NOX3.

    The immunogen is located within amino acids 110 - 160 of NOX3.

    亚型

    IgG
  • 应用备注

    NOX3 antibody can be used for detection of NOX3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    NOX3 antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    NOX3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原

    NOX3 (NADPH Oxidase 3 (NOX3))

    别名

    NOX3

    背景

    The NOX family of NAPDH oxidases is comprised of seven transmembrane proteins that oxidize intracellular NAPDH/NADH, causing electron transport across the membrane and the reduction of molecular oxygen to superoxide (1). NOX3 is expressed predominantly in the inner ear and is involved in the biogenesis of otoconia/otolith (2,3). It has been suggested that NOX3 is activated by the Transient Receptor Potential Vanilloid 1 (TRPV1), and this activity causes increased levels of reactive oxygen species in the inner ear, which in turn leads to STAT1-mediated inflammation and hearing loss (4).

    分子量

    Predicted: 62 kDa

    Observed: 72 kDa

    基因ID

    50508

    NCBI登录号

    NP_056533

    UniProt

    Q9HBY0
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