NOX3 抗体 (AA 110-160)
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北京 101111
Quick Overview for NOX3 抗体 (AA 110-160) (ABIN5690083)
抗原
See all NOX3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 110-160
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特异性
- NOX3 antibody is human and mouse reactive. NOX3 is predicted to not cross-react with other NOX proteins.
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纯化方法
- NOX3 antibody is affinity chromatography purified via peptide column.
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免疫原
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NOX3 antibody was raised against a 15 amino acid peptide near the amino terminus of human NOX3.
The immunogen is located within amino acids 110 - 160 of NOX3. -
亚型
- IgG
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应用备注
- NOX3 antibody can be used for detection of NOX3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- NOX3 antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- NOX3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- NOX3 (NADPH Oxidase 3 (NOX3))
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别名
- NOX3
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背景
- The NOX family of NAPDH oxidases is comprised of seven transmembrane proteins that oxidize intracellular NAPDH/NADH, causing electron transport across the membrane and the reduction of molecular oxygen to superoxide (1). NOX3 is expressed predominantly in the inner ear and is involved in the biogenesis of otoconia/otolith (2,3). It has been suggested that NOX3 is activated by the Transient Receptor Potential Vanilloid 1 (TRPV1), and this activity causes increased levels of reactive oxygen species in the inner ear, which in turn leads to STAT1-mediated inflammation and hearing loss (4).
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分子量
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Predicted: 62 kDa
Observed: 72 kDa -
基因ID
- 50508
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NCBI登录号
- NP_056533
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UniProt
- Q9HBY0
抗原
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