MALT1 抗体 (AA 630-680)
Our Local Distributor
北京 101111
Quick Overview for MALT1 抗体 (AA 630-680) (ABIN5690045)
抗原
See all MALT1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 630-680
-
特异性
- MALT1 antibody is human, mouse and rat reactive. At least two isoforms of MALT1 are known to exist, this antibody will detect both isoforms.
-
纯化方法
- MALT1 antibody is affinity chromatography purified via peptide column.
-
免疫原
-
MALT1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human MALT1.
The immunogen is located within amino acids 630 - 680 of MALT1. -
亚型
- IgG
-
-
-
-
应用备注
- MALT1 antibody can be used for detection of MALT1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- MALT1 antibody is supplied in PBS containing 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- MALT1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
-
-
- MALT1 (Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1))
-
别名
- MALT1
-
背景
- MALT1 was initially identified as a novel gene that was recurrently rearranged in t(11,18)(q21,q21) mucosa-associated lymphoid tissue lymphomas along with the apoptosis inhibitor protein c-IAP2 (1). MALT1, along with the proteins CARMA1 and Bcl10 form an NF-kappaB-activating complex, termed the CBM signalsome, that acts downstream of lymphocyte antigen receptors as well as many other non-lymphoid cell-surface receptors that play a role in multiple cellular functions (2,3). MALT1 has proteolytic activity, and this activity is critical for full NF-kappaB response in T cell activation (4).
-
分子量
-
Predicted: 91 kDa
Observed: 96 kDa -
基因ID
- 10892
-
NCBI登录号
- NP_006776
-
UniProt
- Q9UDY8
-
途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins
抗原
-